Results 31 to 40 of about 32,967 (183)

Diagnóstico diferencial de dengue y chikungunya en pacientes pediátricos

Biomédica: revista del Instituto Nacional de Salud, 2016
Introducción. Las infecciones por el virus del dengue y del chikungunya presentan síntomas clínicos similares, lo cual dificulta el diagnóstico clínico. Además, son transmitidas por los mismos vectores, por lo que en una región puede haber circulación e ...
Eliana Patricia Calvo, Carolina Coronel-Ruiz, Syrley Velazco, Myriam Velandia-Romero, Jaime E. Castellanos   +4 more
doaj   +1 more source

A Portable, Integrated, Sample-In Result-Out Nucleic Acid Diagnostic Device for Rapid and Sensitive Chikungunya Virus Detection

Micromachines
Chikungunya virus, a mosquito-borne virus that causes epidemics, is often misdiagnosed due to symptom similarities with other arboviruses. Here, a portable and integrated nucleic acid-based diagnostic device, which combines reverse transcription-loop ...
Changping Xu, Yalin Chen, Guiying Zhu, Huan Wu, Qi Jiang, Rui Zhang, Beibei Yu, Lei Fang, Zhiwei Wu   +8 more
doaj   +1 more source

Chikungunya virus disease outbreak in Yap State, Federated States of Micronesia.

PLoS Neglected Tropical Diseases, 2017
BackgroundChikungunya virus is a mosquito-borne alphavirus which causes an acute febrile illness associated with polyarthralgia. Beginning in August 2013, clinicians from the Yap State Department of Health in the Federated States of Micronesia (FSM ...
Daniel M Pastula, W Thane Hancock, Martin Bel, Holly Biggs, Maria Marfel, Robert Lanciotti, Janeen Laven, Tai-Ho Chen, J Erin Staples, Marc Fischer, Susan L Hills   +10 more
doaj   +1 more source

SEROPREVALENCE OF MOSQUITO-BORN AND TICK-BORN MICROORGANISMS IN HUMAN POPULATION OF SOUTH BACKA DISTRICT

Archives of Veterinary Medicine, 2016
Chikungunya virus is an Arbo virus belonging to the family Togaviridae. In urban areas, antropophilic Aedes aegypti and Aedes albopictus mosquitoes are vectors for virus transmission to human population.
Ivana Hrnjaković Cvjetković, Tamaš Petrović, Dušan Petrić, Dejan Cvjetković, Gordana Kovačević, Jelena Radovanov, Aleksandra Jovanović Galović, Aleksandra Pat, Nataša Nikolić, Sandra Stefan Mikić, Vesna Milošević   +10 more
doaj   +1 more source

Zebrafish and CRISPR—A synergistic approach to decipher and cure human diseases

Animal Models and Experimental Medicine, EarlyView.
Zebrafish, with high genetic homology to humans, serves as a powerful vertebrate model for disease modeling and drug discovery. Integration of CRISPR/Cas9 technology enables precise genome editing, facilitating the development of translational models for human diseases.
Manikandan Sivaprakasam, Aashika Raagavi Jeanpierre, Salma Mohammed, Rajesh Srinivasan, Aman Kumar Mohanty   +4 more
wiley   +1 more source

Healthcare workers knowledge and diagnostic practices: a need for dengue and chikungunya training in Moshi Municipality, Kilimanjaro Tanzania

BMC Research Notes, 2019
Objective Dengue and chikungunya virus diseases are becoming an increasingly important global health threats and are continuously expanding their geographical range.
Samwel Saringe, Debora C. Kajeguka, Dickson D. Kagirwa, Maseke R. Mgabo, Basiliana Emidi   +4 more
doaj   +1 more source

Design Space Assessment of Virus Inactivation in Plasma‐Derived Matrices Establishes a Single Detergent Alternative to TX‐100‐Containing Mixes

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The detergent Triton X‐100 (TX‐100) is a typical component of solvent/detergent (S/D) mixes applied for virus inactivation steps of biomanufacturing processes, yet environmentally unfavorable properties have led to restrictions on its use. Deviron 13‐S9 has recently been described as an eco‐friendly TX‐100 alternative, with powerful virus ...
Johanna Kindermann, Cecilie Klausen, Michael Karbiener, Thomas R. Kreil   +3 more
wiley   +1 more source

A vaccinia-based single vector construct multi-pathogen vaccine protects against both Zika and chikungunya viruses

Nature Communications, 2018
Zika and chikungunya virus are co-circulating in many regions and currently there is no approved vaccine for either virus. Here, the authors engineer one vaccinia virus based vaccine for both, Zika and chikungunya, and show protection from infection and ...
Natalie A. Prow, Liang Liu, Eri Nakayama, Tamara H. Cooper, Kexin Yan, Preethi Eldi, Jessamine E. Hazlewood, Bing Tang, Thuy T. Le, Yin Xiang Setoh, Alexander A Khromykh, Jody Hobson-Peters, Kerrilyn R. Diener, Paul M. Howley, John D. Hayball, Andreas Suhrbier   +15 more
doaj   +1 more source

Chikungunya myeloradiculopathy: A rare complication

Journal of Global Infectious Diseases, 2012
Chikungunya, an alpha virus belonging to the family of Togaviridae is transmitted to humans by the bite of Aedes aegypti mosquito and presents with fever, headache, rash, and severe arthralgia.
Mohana Krishnan, Rahul, Krishnamoorthy
doaj   +1 more source

Maltase 1 regulates DENV2 infection and life history in Aedes aegypti

Insect Science, EarlyView.
Our study employed CRISPR/Cas9 to generate a MAL1 knockout strain of Aedes aegypti, demonstrating that the absence of MAL1 significantly suppresses DENV2 replication in the midgut and impairs viral transmission. The mutation also altered life‐history (hatching/pupation/emerging rates and sex‐specific survival), identifying MAL1 as a novel target for ...
Man‐Jin Li, Jin Cheng, Ya‐Ming Zou, Quan‐Chao Liu, Ding Zhu, Ce‐Jie Lan   +5 more
wiley   +1 more source