Results 51 to 60 of about 1,152,519 (197)

Dimerization of human PARP15 is required for NAD+ binding and automodification

The FEBS Journal, EarlyView.
This study provides an integrated structural model of human PARP15. Biophysical, enzymatic, and cell‐based analyses identify the dimer as the active oligomeric state capable of binding the substrate NAD+. A co‐crystal structure with a non‐hydrolyzable substrate analog BAD reveals the molecular basis for the dimerization requirement.
Anna Tuovinen, Johan Pääkkönen, Mirko M. Maksimainen, Lea Hirschen, Heli I. Hentilä, Marie Tauscher, Bernhard Lüscher, Carlos Vela‐Rodríguez, Patricia Korn, Lari Lehtiö   +9 more
wiley   +1 more source

Using mathematical transmission modelling to investigate drivers of respiratory syncytial virus seasonality in children in the philippines [PDF]

, 2013
We used a mathematical transmission model to estimate when ecological drivers of respiratory syncytial virus (RSV) transmissibility would need to act in order to produce the observed seasonality of RSV in the Philippines.
Simoes, Eric A. F., Lucero, M., Weinstein, P., Lucero, Marilla G., Lucero, Marilla G, Simões, E., Paynter, Stuart, Yakob, L., Laith Yakob, Marilla G. Lucero, Williams, Gail, Eric A. F. Simões, Nohynek Hanna, Sly, Peter D., Peter D Sly, Peter D. Sly, Tallo, V., Simões Eric A. F., Tallo, Veronica, Gail Williams, Yakob Laith, Weinstein, Philip, Weinstein Philip, Nohynek, Hanna, Ware Robert S., Ware, R., Ware, Robert S., Paynter, S., Philip Weinstein, Tallo Veronica, Robert S Ware, Paynter Stuart, Marilla G Lucero, Veronica Tallo, Ware, Robert S, Yakob, Laith, Sly, P., Sly Peter D., Williams, G., Eric A F Simões, Lucero Marilla G., Robert S. Ware, Simões, Eric AF, Williams Gail, Sly, Peter D, Hanna Nohynek, Stuart Paynter, Nohynek, H.   +47 more
core   +1 more source

Preimaginal development of Aedes aegypti L. (Diptera: Culicidae) in brackish water gives rise to adult mosquitoes with thicker cuticles and greater insecticide resistance

Medical and Veterinary Entomology, EarlyView.
The principal arboviral vector Aedes aegypti can develop in coastal brackish water field habitats (0.5–15 g/L salt) with larvae possessing thicker cuticles and greater resistance to the larvicide Temephos. Females emerging from brackish water‐developing preimaginal stages are now shown to have thicker and remodelled leg and abdominal cuticles and ...
Kokila Sivabalakrishnan, Andrew Hemphill, S. H. P. Parakrama Karunaratne, Arunasalam Naguleswaran, Isabel Roditi, Sinnathamby N. Surendran, Ranjan Ramasamy   +6 more
wiley   +1 more source

High seroprevalence of IgM antibodies against chikungunya among patients with acute febrile illness seeking healthcare in a malaria-endemic area in the Afar Region, Northeast Ethiopia

SAGE Open Medicine
Objective: Chikungunya is a disease caused by Aedes mosquito-borne chikungunya virus infection. This disease is becoming one of the emerging/re-emerging viral diseases in tropical and subtropical countries but is neglected by public health systems.
Biruk Zerfu, Tesfu Kassa, Gezahegne Mamo, James W Larrick, Mengistu Legesse   +4 more
doaj   +1 more source

Investigating the association between weather variables and Aedes albopictus abundance in Windsor, Ontario

Medical and Veterinary Entomology, EarlyView.
Trapping completed by Windsor‐Essex County Health Unit. Data analysis using trap and weather data. Canadian weather thresholds are associated with increased mosquito abundance. Abstract Aedes albopictus (Diptera: Culicidae) is notorious for transmitting several pathogens of public health importance.
Keana Shahin, Katie M. Clow, Olaf Berke, Ilaria Dorigatti, Victoria Ng   +4 more
wiley   +1 more source

Emergent chikungunya virus and arthritis in the Americas

, 2015
The Correspondence letter by Emilie Javelle and colleagues emphasises new insights into arthritic disease after chikungunya virus infection. We are gratified that new evidence is confirming our argument that chikungunya virus is likely to exacerbate or ...
Mahalingam, Suresh, Foo, Suan Sin, Rolph, Michael S   +2 more
core   +1 more source

Impact of bauxite mining on mosquito communities (Diptera: Culicidae) and pathogen transmission risks in the eastern Amazon

Medical and Veterinary Entomology, EarlyView.
Bauxite mining in the Amazon alters mosquito communities, favouring anthropophilic and generalist vectors while reducing species diversity and the variety of blood meal sources. Molecular analyses identified humans, tapirs and deer as the primary blood meal sources.
Mayron Mielly Morais Pacheco, Poliana da Silva Lemos, Mônica Silva Coelho, Tatiane Marques Porangaba de Oliveira, Luciano Chaves Franco Filho, Øystein Wiig, Ana Cristina Mendes‐Oliveira, Leonardo Sena, Maria Anice Mureb Sallum   +8 more
wiley   +1 more source

Chikungunya Virus Infections

, 2015
Comment on Chikungunya virus and the global spread of a mosquito-borne disease. [N Engl J Med. 2015] Chikungunya Virus Infections. [N Engl J Med. 2015] Chikungunya Virus Infections. [N Engl J Med.
Weaver, Scott, Lecuit, Marc
core   +1 more source

Shared and Distinguishing Features of Late‐Onset Rheumatic Diseases Fulfilling Polymyalgia Rheumatica Classification Criteria

Arthritis &Rheumatology, EarlyView.
Kerem Abacar, Ala Altaie, Andrew Barr, Sarah L. Mackie, Kulveer Mankia, Dennis McGonagle   +5 more
wiley   +1 more source

Relationships between meteorological factors and mosquito vector density in an Urban District of Shanghai, China (2018–2024)

Medical and Veterinary Entomology, EarlyView.
The effect of temperature on oviposition activity is not uniform across time. Heat stress exerts delayed population‐level impacts. Moderate temperatures favour population development while both low and high temperatures impose constraints. The delayed negative effect of warm temperatures, peaking at 2–3 weeks rather than immediately.
Haijian Wang, Yi Zhang, Chunwei Sun, Yingyu Yang, Miaomiao He, Zhixin Wu, Jianguo Tan, Fan He   +7 more
wiley   +1 more source