Results 61 to 70 of about 1,757,770 (311)

Structural basis of Chikungunya virus inhibition by monoclonal antibodies

Proceedings of the National Academy of Sciences of the United States of America, 2020
Significance Chikungunya virus (CHIKV) is a significant human pathogen that causes debilitating and long-lasting arthritis. Currently, there is no approved vaccine or specific therapeutic.
Q. Zhou, J. Fox, J. T. Earnest, T. Ng, A. S. Kim, G. Fibriansah, V. Kostyuchenko, Jian Shi, B. Shu, M. Diamond, S. Lok   +10 more
semanticscholar   +1 more source

Reemergence of Chikungunya Virus [PDF]

Journal of Virology, 2014
ABSTRACT Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus that causes acute fever and acute and chronic musculoskeletal pain in humans. Since 2004, CHIKV has caused millions of cases of disease in the Indian Ocean region and has emerged in new areas, including Europe, the Middle East, and the Pacific region. The mosquito vectors
openaire   +2 more sources

Chikungunya myeloradiculopathy: A rare complication

Journal of Global Infectious Diseases, 2012
Chikungunya, an alpha virus belonging to the family of Togaviridae is transmitted to humans by the bite of Aedes aegypti mosquito and presents with fever, headache, rash, and severe arthralgia.
Mohana Krishnan, Rahul, Krishnamoorthy
doaj   +1 more source

Tomatidine, a natural steroidal alkaloid shows antiviral activity towards chikungunya virus in vitro

Scientific Reports, 2020
In recent decades, chikungunya virus (CHIKV) has re-emerged, leading to outbreaks of chikungunya fever in Africa, Asia and Central and South America. The disease is characterized by a rapid onset febrile illness with (poly)arthralgia, myalgia, rashes ...
Berit Troost, L. Mulder, Mayra Diosa-Toro, Denise P. I. van de Pol, Izabela A. Rodenhuis-Zybert, J. Smit   +5 more
semanticscholar   +1 more source

Antiviral Strategies Against Chikungunya Virus [PDF]

, 2016
In the last few decades the Chikungunya virus (CHIKV) has evolved from a geographically isolated pathogen to a virus that is widespread in many parts of Africa, Asia and recently also in Central- and South-America. Although CHIKV infections are rarely fatal, the disease can evolve into a chronic stage, which is characterized by persisting ...
Abdelnabi, Rana, Neyts, Johan, Delang, Leen   +2 more
openaire   +3 more sources

Healthcare workers knowledge and diagnostic practices: a need for dengue and chikungunya training in Moshi Municipality, Kilimanjaro Tanzania

BMC Research Notes, 2019
Objective Dengue and chikungunya virus diseases are becoming an increasingly important global health threats and are continuously expanding their geographical range.
Samwel Saringe, Debora C. Kajeguka, Dickson D. Kagirwa, Maseke R. Mgabo, Basiliana Emidi   +4 more
doaj   +1 more source

Current Efforts in the Development of Vaccines for the Prevention of Zika and Chikungunya Virus Infections

Frontiers in Immunology, 2020
Arboviruses represent major challenges to public health, particularly in tropical, and subtropical regions, and a substantial risk to other parts of the world as respective vectors extend their habitats.
Sabrina Schrauf, Roland Tschismarov, Erich Tauber, Katrin Ramsauer   +3 more
semanticscholar   +1 more source

A Portable, Integrated, Sample-In Result-Out Nucleic Acid Diagnostic Device for Rapid and Sensitive Chikungunya Virus Detection

Micromachines
Chikungunya virus, a mosquito-borne virus that causes epidemics, is often misdiagnosed due to symptom similarities with other arboviruses. Here, a portable and integrated nucleic acid-based diagnostic device, which combines reverse transcription-loop ...
Changping Xu, Yalin Chen, Guiying Zhu, Huan Wu, Qi Jiang, Rui Zhang, Beibei Yu, Lei Fang, Zhiwei Wu   +8 more
doaj   +1 more source

Diagnóstico diferencial de dengue y chikungunya en pacientes pediátricos

Biomédica: revista del Instituto Nacional de Salud, 2016
Introducción. Las infecciones por el virus del dengue y del chikungunya presentan síntomas clínicos similares, lo cual dificulta el diagnóstico clínico. Además, son transmitidas por los mismos vectores, por lo que en una región puede haber circulación e ...
Eliana Patricia Calvo, Carolina Coronel-Ruiz, Syrley Velazco, Myriam Velandia-Romero, Jaime E. Castellanos   +4 more
doaj   +1 more source

Post–Chikungunya Virus Infection Musculoskeletal Disorders: Syndromic Sequelae after an Outbreak

Tropical Medicine and Infectious Disease, 2021
The Chikungunya virus is a re-emerging mosquito-borne alphavirus. Outbreaks are unpredictable and explosive in nature. Fever, arthralgia, and rash are common symptoms during the acute phase.
Hisham A. Imad, Wasin Matsee, Sajikapon Kludkleeb, Punyisa Asawapaithulsert, Juthamas Phadungsombat, Emi E. Nakayama, Keita Suzuki, Pornsawan Leaungwutiwong, Watcharapong Piyaphanee, Weerapong Phumratanaprapin, Tatsuo Shioda   +10 more
doaj   +1 more source