Results 211 to 220 of about 14,798 (236)

Osteoclastogenesis induced by CHIKV-infected fibroblast-like synoviocytes: a possible interplay between synoviocytes and monocytes/macrophages in CHIKV-induced arthralgia/arthritis.

open access: yesVirus Research, 2013
Fibroblast-like synoviocytes are known to migrate from joint to joint and are proposed to be one of the key players in the inflammatory cascade amplification in rheumatoid arthritis patients. In the recent CHIKV epidemic, patients developed arthritis-like syndrome and the synoviocyte is one of the suspected players in CHIKV-induced polyarthritis. Thus,
W. Phuklia   +7 more
semanticscholar   +4 more sources
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Clinical, Virological, and Immunological Profiles of DENV, ZIKV, and/or CHIKV-Infected Brazilian Patients

Intervirology, 2020
Background: Arboviruses co-circulating within a population that are transmitted by the same vector have the potential to cause coinfections. Coinfections with dengue virus (DENV), Zika virus (ZIKV), and chikungunya virus (CHIKV) have been occurring in ...
J. C. Sánchez-Arcila   +11 more
semanticscholar   +1 more source

Proteomic analysis of CHIKV‐infected human fibroblast‐like synoviocytes: Identification of host factors potentially associated with CHIKV replication and cellular pathogenesis

Microbiology and Immunology, 2020
AbstractChikungunya virus (CHIKV) is a mosquito‐borne virus that causes arthralgic fever. Fibroblast‐like synoviocytes play a key role in joint damage in inflammatory arthritides and can additionally serve as target cells for CHIKV infection. To gain a better understanding of CHIKV‐induced arthralgia, the interaction between CHIKV and synoviocytes was ...
Apamas Sukkaew   +4 more
openaire   +2 more sources

Analysis of within-host CHIKV dynamics models with general incidence rate

International Journal of Biomathematics, 2018
In this paper we study the stability analysis of two within-host Chikungunya virus (CHIKV) dynamics models. The incidence rate between the CHIKV and the uninfected monocytes is modeled by a general nonlinear function. The second model considers two types
A. Elaiw, T. Alade, Saud M. Alsulami
semanticscholar   +1 more source

Experience of Perinatal and Neonatal Chikungunya Virus (CHIKV) Infection in a Tertiary Care Neonatal Centre during Outbreak in North India in 2016: A Case Series

Journal of Tropical Pediatrics, 2018
BACKGROUND In 2016, there was a massive outbreak of chikungunya in North India. During the epidemic, we observed many neonatal and early infantile cases of chikungunya, with a probable perinatal transmission.
Surender Kumar   +6 more
semanticscholar   +1 more source

Blunting CHIKV infection by keeping T cells in check

Science Translational Medicine, 2017
Modulating the host immune response ameliorates arthritic disease in mice infected with chikungunya virus (Miner et al . and Teo et al .).
Philippe, Gasque   +1 more
openaire   +2 more sources

Chicungnya, CHIKV, Chikungunya o Chicunguña

2016
El aula de clase, la investigacion y el momento que vive Colombia con una enfermedad denominada Chicunguna o Chicungunya fueron las grandes herramientas para conocer en que consiste y por que los pacientes se sienten desprotegidos, desesperados, sin respuesta a una enfermedad por la cual solamente reciben como medicamento acetaminofen y muchas ...
Amparo Aurora Ramírez-Tamayo   +1 more
openaire   +1 more source

Chikungunya Virus (CHIKV): Coming to America

Biosafety, 2014
Chikungunya Virus (CHIKV) is an arbovirus of the alphavirus genus (Togaviridae family) transmitted by the bite of infected Aedes mosquitoes. The word, Chikungunya, translates to “that which bends up”, based on the stooped position of patients during the rheumatic symptoms of the disease.
openaire   +1 more source

Novel Therapeutic Strategy Suppresses Mosquito Saliva-Enhanced CHIKV Infection

2021
Chikungunya virus (CHIKV) is one of the most important emerging infectious diseases and is responsible for significant global public health problems due to its recent outbreaks which was associated with severe morbidity. Transmission of CHIKV occurs through a bite by infected Aedes aegypti or Aedes albopictus.
Ting Qi Yong, JiaXin Xiao
openaire   +1 more source

Identification of CHIKV biomarkers in serum of CHIKV-infected mice and a high affinity ssDNA aptamer against E2 as bioreceptor for diagnosis.

2021
Chikungunya virus (CHIKV) which is mosquito-borne, causes fever and joint pain in human. Diagnosis of CHIKV infection is via laboratory detection of viral genes and antibodies requiring specialized instruments and technical skills, which are unsuitable for point-of-care diagnosis.
openaire   +2 more sources

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