Wolbachia and arbovirus inhibition in mosquitoes [PDF]
, 2013 Wolbachia is a maternally inherited intracellular bacteria that can manipulate the reproduction of their insect hosts, and cytoplasmic incompatibility allows them to spread through mosquito populations.
Sinkins, Steven P.
core +1 more source
Large-scale outbreak of Chikungunya virus infection in Thailand, 2018-2019.
PLoS ONE, 2021 Between 2018 and 2019, the incidence of chikungunya was approximately 15,000 cases across 60 provinces in Thailand. Here, the clinical presentations in chikungunya, emergent pattern, and genomic diversity of the chikungunya virus (CHIKV) causing this ...
Sarawut Khongwichit +6 more
doaj +1 more source
Molecular Therapy: Nucleic Acids, 2022 The arthritogenic alphavirus, chikungunya virus (CHIKV), is now present in almost 100 countries worldwide. Further spread is very likely, which raises public health concerns. CHIKV infections cause fever and arthralgia, which can be debilitating and last
Christin Schmidt +6 more
doaj +1 more source
Mutations in the E2 glycoprotein and the 3\u27 untranslated region enhance chikungunya virus virulence in mice [PDF]
, 2017 Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus that causes debilitating musculoskeletal pain and inflammation and can persist for months to years after acute infection.
Carpentier, Kathryn S +8 more
core +3 more sources
Unbiased Metagenomic Sequencing for Pediatric Meningitis in Bangladesh Reveals Neuroinvasive Chikungunya Virus Outbreak and Other Unrealized Pathogens. [PDF]
, 2019 The burden of meningitis in low-and-middle-income countries remains significant, but the infectious causes remain largely unknown, impeding institution of evidence-based treatment and prevention decisions.
Crawford, Emily D. +25 more
core +2 more sources
mBio, 2017 Mosquito-transmitted chikungunya virus (CHIKV) is an arthritogenic alphavirus of the Togaviridae family responsible for frequent outbreaks of arthritic disease in humans.
Adam Taylor +7 more
doaj +1 more source
Analysis of latent CHIKV dynamics models with general incidence rate and time delays
Journal of Biological Dynamics, 2018 In this paper, we study the stability analysis of latent Chikungunya virus (CHIKV) dynamics models. The incidence rate between the CHIKV and the uninfected monocytes is modelled by a general nonlinear function which satisfies a set of conditions.
A. Elaiw, T. Alade, Saud M. Alsulami
semanticscholar +1 more source
Zika virus: New clinical syndromes and its emergence in the western hemisphere [PDF]
, 2016 Zika virus (ZIKV) had remained a relatively obscure flavivirus until a recent series of outbreaks accompanied by unexpectedly severe clinical complications brought this virus into the spotlight as causing an infection of global public health concern.
Brazilian Medical Genetics Society–Zika Embryopathy Task Force +9 more
core +3 more sources
Unique epitopes recognized by antibodies induced in Chikungunya virus-infected non-human primates: implications for the study of immunopathology and vaccine development. [PDF]
PLoS ONE, 2014 Chikungunya virus (CHIKV) is an Alphavirus that causes chronic and incapacitating arthralgia in humans. Although patient cohort studies have shown the production of CHIKV specific antibodies, the fine specificity of the antibody response against CHIKV is
Yiu-Wing Kam +7 more
doaj +1 more source
Specific detection of dengue and Zika virus antibodies using envelope proteins with mutations in the conserved fusion loop [PDF]
, 2017 Detection of antibodies is widely used for the diagnosis of infections with arthropod-borne flaviviruses including dengue (DENV) and Zika virus (ZIKV). Due to the emergence of ZIKV in areas endemic for DENV, massive co-circulation is observed and methods
Barzon, Luisa +12 more
core +2 more sources