Results 51 to 60 of about 15,961 (231)

CHIKV replicates independently of mitophagy.

, 2023
(A) Representative fluorescence microscopy images, (B) quantification of the mitolysosomes/cell and (C) percentage of infection in U2OS-Cox-8 GFP-mCherry cells reverse transfected with siBNIP3 or siScramble for 48 h and either mock-treated, infected with
Liliana Echavarria-Consuegra (17458509), Mario Mauthe (5449997), Jolanda M. Smit (9220676), Denise Van de Pol (17458512), Nilima Dinesh Kumar (11701925), Fulvio Reggiori (90842), Marleen van der Laan (13961885)   +6 more
core   +1 more source

Diagnostic Accuracy of Real Time Reverse Transcriptase Polymerase Chain Reaction for Chikungunya Virus Detection: A Systematic Review and Meta‐Analysis

Tropical Medicine &International Health, EarlyView.
ABSTRACT Background Chikungunya virus (CHIKV) is an arbovirus that causes an acute febrile illness with intense muscle and joint pain, with the possibility of progressing to a chronic or neurological stage. We conducted a systematic review and meta‐analysis with the aim of evaluating the accuracy of real‐time reverse transcriptase polymerase chain ...
Róger J. Costa, Cleyde S. C. Marconi, Gleice K. Jesus, Gabriel O. Franco, Abevailton M. Silva, Maria B. Arriaga, Gúbio C. Soares, Silvia I. Sardi, Eduardo M. Netto   +8 more
wiley   +1 more source

CHIKV-associated disease in adults vs aged mice.

, 2019
Adult and aged C57BL/6J mice were infected with 105 CCID50 per mouse of CHIKV LR2006-OPY1 via subcutaneous injection of the right hind footpad and monitored for 14 days.
Ted M. Ross (43118), Ying Huang (53474), Cheryl A. Jones (3092946), Maria T. Arévalo (6640280)   +3 more
core   +1 more source

The Comparative Effectiveness of Vector Control Approaches for Dengue: A Systematic Review and Multilevel Network Meta‐Analysis

Tropical Medicine &International Health, EarlyView.
ABSTRACT Background Dengue vector control plays an important role in reducing the burden of dengue infection. Conventional meta‐analysis can only include interventions that can be directly compared. Hence, this study aimed to compare the effectiveness of all interventions for dengue vector control directly and indirectly through a multilevel Bayesian ...
Gary K. K. Low, Yuling Ke, Emmanuel Samson, Prutha Rane, Olaf Horstick, Carlos Alberto Montenegro‐Quiñonez   +5 more
wiley   +1 more source

Challenges in Surveillance for Chikungunya Virus (CHIKV) Infection

Online Journal of Public Health Informatics, 2015
We describe challenges and lessons learned using biosurveillance methods for identifying Chikungunya (CHIKV) infections. Surveillance was performed using VA ESSENCE, electronic laboratory data and facility reports. As of Aug. 14, 2014, 21 confirmed/probable cases were identified at 10 hospitals.
Lucero-Obusan, Cynthia A., Schirmer, Patricia, Oda, Gina, Holodniy, Mark   +3 more
openaire   +2 more sources

Anopheles cell lines infected with CHIKV, ONNV, and CHIKV/ONNVnsP3.

, 2023
(A) Viruses used in this study. The structures of CHIKV, ONNV, and recombinant CHIKV/ONNVnsP3 that has a CHIKV backbone with the nsP3 from ONNV are shown. Adapted from [11].
Paul L. Burns (14504490), Jeremy P. Ledermann (9120580), Jan Pohl (177453), Ann M. Powers (8463522), Matthew S. Reed (9420497), Olga Stuchlik (177449), Nathaniel M. Byers (14504487)   +6 more
core   +1 more source

Chikungunya virus neutralization antigens and direct cell-to-cell transmission are revealed by human antibody-escape mutants.

PLoS Pathogens, 2011
Chikungunya virus (CHIKV) is an alphavirus responsible for numerous epidemics throughout Africa and Asia, causing infectious arthritis and reportedly linked with fatal infections in newborns and elderly.
Chia Yin Lee, Yiu-Wing Kam, Jan Fric, Benoit Malleret, Esther G L Koh, Celine Prakash, Wen Huang, Wendy W L Lee, Cui Lin, Raymond T P Lin, Laurent Renia, Cheng-I Wang, Lisa F P Ng, Lucile Warter   +13 more
doaj   +1 more source

Virus‐specific alterations in placental structure and transporter expression following maternal arbovirus infection

The Journal of Physiology, EarlyView.
Abstract figure legend Arboviruses induce virus‐specific alterations in placental structure and functional markers. Chikungunya virus (CHIKV) exposure was associated with reduced syncytiotrophoblast and syncytial knot areas, increased cytotrophoblast proliferation (Ki‐67) and thyroid transporter (MCT8) expression, reduced protective (P‐gp and BCRP ...
Cherley B. V. Andrade, Enrrico Bloise, Natália L. Silva, Jair R. S. Braga, Sharton V. A. Coelho, Veronica M. O. Nascimento, Guinever E. Imperio, Camila O. S. Nunes, Antônio J. L. A. Cunha, Marcelo A. Pascoal‐Xavier, Luciana B. Arruda, Arnaldo Prata‐Barbosa, Kristin L. Connor, Tania M. Ortiga‐Carvalho   +13 more
wiley   +1 more source

Nonstructural Protein 2 (nsP2) of Chikungunya Virus (CHIKV) Enhances Protective Immunity Mediated by a CHIKV Envelope Protein Expressing DNA Vaccine [PDF]

Viral Immunology, 2013
Chikungunya virus (CHIKV) is an important emerging mosquito-borne alphavirus, indigenous to tropical Africa and Asia. It can cause epidemic fever and acute illness characterized by fever and arthralgias. The epidemic cycle of this infection is similar to dengue and urban yellow fever viral infections.
Bao, Huihui, Ramanathan, Aarti A., Kawalakar, Omkar, Sundaram, Senthil G., Tingey, Colleen, Bian, Charoran B., Muruganandam, Nagarajan, Vijayachari, Paluru, Sardesai, Niranjan Y., Weiner, David B., Ugen, Kenneth E., Muthumani, Karuppiah   +11 more
openaire   +3 more sources

Characteristics of viremic CHIKV infected and CHIKV- patients^a.

, 2016
Characteristics of viremic CHIKV infected and CHIKV- patientsa.
Ingrid Krishnadath (3174195), Malti R. Adhin (740076), Rachel Sno (3174189), Meritha G. Grunberg (3174192), Wilco Zijlmans (3174198), Farah T. van Genderen (3174186)   +5 more
core   +1 more source