Results 41 to 50 of about 15,961 (231)

Chikungunya virus populations experience diversity- dependent attenuation and purifying intra-vector selection in Californian Aedes aegypti mosquitoes.

PLoS Neglected Tropical Diseases, 2019
Chikungunya virus (Togaviridae, Alphavirus; CHIKV) is a mosquito-borne global health threat that has been transmitted transiently in the southeastern United States.
Kasen K Riemersma, Lark L Coffey
doaj   +1 more source

Cytokines and Chemokines in Chikungunya Virus Infection: Protection or Induction of Pathology

Pathogens, 2020
Chikungunya virus (CHIKV) infection has been commonly detected in tropical countries. The clinical manifestations of CHIKV infection are similar to those of rheumatoid arthritis.
Chintana Chirathaworn, Jira Chansaenroj, Yong Poovorawan   +2 more
doaj   +1 more source

Dimerization of human PARP15 is required for NAD+ binding and automodification

The FEBS Journal, EarlyView.
This study provides an integrated structural model of human PARP15. Biophysical, enzymatic, and cell‐based analyses identify the dimer as the active oligomeric state capable of binding the substrate NAD+. A co‐crystal structure with a non‐hydrolyzable substrate analog BAD reveals the molecular basis for the dimerization requirement.
Anna Tuovinen, Johan Pääkkönen, Mirko M. Maksimainen, Lea Hirschen, Heli I. Hentilä, Marie Tauscher, Bernhard Lüscher, Carlos Vela‐Rodríguez, Patricia Korn, Lari Lehtiö   +9 more
wiley   +1 more source

Susceptibility of six different cell lines infected with three Chikungunya strains–CHIKV-122508, CHIKV-6708 and CHIKV-0708.

, 2019
Cells were infected with different CHIKV strains across various timepoints. (A) SJCRH30, (B) SK-N-SH, (C) HeLa CCL2, (D) BHK-21, (E) C2C12 and (F) C6/36.
Khairunnisa Mohamed Hussain (7310264), Justin Jang Hann Chu (7310267), Ching Hua, Regina Lee (7310261)   +2 more
core   +1 more source

Comodulation of Dengue and Chikungunya Virus Infection During a Coinfection Scenario in Human Cell Lines

Frontiers in Cellular and Infection Microbiology, 2022
The Dengue virus (DENV) and Chikungunya virus (CHIKV) are the arboviruses that pose a threat to global public health. Coinfection and antibody-dependent enhancement are major areas of concern during DENV and CHIKV infections, which can alter the clinical
Debjani Taraphdar, Bharati Singh, Bharati Singh, Sabyasachi Pattanayak, Avula Kiran, Avula Kiran, Poornima Kokavalla, Mohd. Faraz Alam, Mohd. Faraz Alam, Gulam Hussain Syed   +9 more
doaj   +1 more source

Impact of bauxite mining on mosquito communities (Diptera: Culicidae) and pathogen transmission risks in the eastern Amazon

Medical and Veterinary Entomology, EarlyView.
Bauxite mining in the Amazon alters mosquito communities, favouring anthropophilic and generalist vectors while reducing species diversity and the variety of blood meal sources. Molecular analyses identified humans, tapirs and deer as the primary blood meal sources.
Mayron Mielly Morais Pacheco, Poliana da Silva Lemos, Mônica Silva Coelho, Tatiane Marques Porangaba de Oliveira, Luciano Chaves Franco Filho, Øystein Wiig, Ana Cristina Mendes‐Oliveira, Leonardo Sena, Maria Anice Mureb Sallum   +8 more
wiley   +1 more source

Peptide aptamer-based time-resolved fluoroimmunoassay for CHIKV diagnosis

Virology Journal, 2023
Abstract Background Chikungunya virus (CHIKV) and Dengue virus (DENV) have similar clinical symptoms, which often induce misdiagnoses. Therefore, an antigen detection diagnostic system that can clearly identify these two viruses is desirable.
Tonggong Liu, Cheng Gao, Jingzhe Wang, Jianning Song, Xi Chen, Hongfang Chen, Xiaona Zhao, Huanwen Tang, Dayong Gu   +8 more
openaire   +3 more sources

Neutralization titers against CHIKV-S27 and CHIKV-IND/NL10.

, 2014
Neutralization titers against CHIKV-S27 and CHIKV-IND/NL10.
Varsha D. Sewbalaksing (625682), Gerd Sutter (181175), Ingeborg van Middelkoop (625683), Gorben P. Pijlman (342864), Asisa Volz (181161), Jouke M. Roose (162117), Byron E. E. Martina (162110), Petra van den Doel (352711), Albert D. M. E. Osterhaus (138961), Vincent Duiverman (625684), Eva van de Wetering (625685)   +10 more
core   +1 more source

Abundance and species diversity of mosquitoes (Diptera, Culicidae) in endemic areas for arboviruses in the Eastern Amazon, Brazil Abundância e diversidade de espécies de mosquitos (Diptera, Culicidae) em áreas endêmicas para arboviroses na Amazônia Oriental, Brasil

Medical and Veterinary Entomology, EarlyView.
A total of 3671 adult specimens of Culicidae were identified, comprising 35 species distributed across 11 genera. Species of the genera Anopheles, Aedes, Psorophora, Haemagogus, Culex, Coquillettidia and Mansonia were identified in both localities and are considered of medical and epidemiological importance in the transmission of arboviruses ...
Everson dos Santos David, Shirley Vasconcelos Komninakis, Letice Lima da Silva, Erique da Costa Fonseca, Karen Carmo dos Santos, Ledayane Mayana Costa Barbosa, Raimundo Nonato Picanço Souto   +6 more
wiley   +1 more source

Discovery of Mosquito Saliva MicroRNAs during CHIKV Infection

PLOS Neglected Tropical Diseases, 2015
Mosquito borne pathogens are transmitted to humans via saliva during blood feeding. Mosquito saliva is a complex concoction of many secretory factors that modulate the feeding foci to enhance pathogen infection and establishment. Multiple salivary proteins/factors have been identified/characterized that enhance pathogen infection.
Payal D Maharaj, Steven G Widen, Jing Huang, Thomas G Wood, Saravanan Thangamani   +4 more
openaire   +4 more sources