Results 91 to 100 of about 231,928 (217)

Missense Variants in the A Isoform of FGF13 as a Novel Cause of Paroxysmal Dyskinesia

Movement Disorders, EarlyView.
Abstract Background Pathogenic variants within the unique N‐terminal inactivation particle of FGF13 isoform A (FGF13A) have so far been associated only with an X‐linked dominant epileptic encephalopathy (DEE). Objective The aim was to expand the clinical and molecular spectrum of FGF13A‐related disorder.
Cyril Mignot, Matthildi Athina Papathanasiou Terzi, Claudia Ravelli, Elisabeth Bosch, Xueqin Lin, Adeline Trauffler, Roseline Caumes, Andrew E. Fry, Clementine Fort, Gaelle Gauthe, Regina Trollmann, Thomas Wirth, Mathieu Anheim, Aurélie Méneret, Emmanuel Roze, Jean‐Madeleine de Sainte Agathe, Hailan He, Eleni Panagiotakaki, Gaëtan Lesca, André Reis, Diane Doummar, Thomas Smol, Georgia Vasileiou   +22 more
wiley   +1 more source

Feasibility of an Online Resilience Program for Mothers With Adverse Childhood Experiences

Research in Nursing &Health, EarlyView.
ABSTRACT Enhancing maternal resilience through targeted interventions has emerged as a promising strategy for preventing the intergenerational transmission of adverse childhood experiences (ACEs). This study aimed to develop and evaluate the feasibility of an online resilience program tailored for mothers with ACEs.
Hyeseon Yun, Eun Kyoung Choi
wiley   +1 more source

Association of Preoperative Inflammatory Markers With Preoperative Anxiety and Emergence Agitation in Children

Pediatric Anesthesia, EarlyView.
ABSTRACT Introduction Emergence agitation (EA) is a postoperative neurobehavioral complication characterized by a transient disturbance in cognition and perception following anesthesia. Neuroinflammation is thought to play a central role in its pathophysiology.
Nezahat Merve Ata Soylu, Zehra Hatipoglu, Ersel Gulec, Mediha Turktan, Nurefsan Sadıkoglu, Yusuf Kemal Arslan, Dilek Ozcengiz   +6 more
wiley   +1 more source

Pharmacokinetics of Intravenous Melatonin in Preschool‐Aged Pediatric Surgical Patients

Pediatric Anesthesia, EarlyView.
ABSTRACT Background Melatonin may have several beneficial clinical effects in the perioperative setting. In children, it has been studied for preoperative anxiety, postoperative pain, and emergence delirium. Melatonin's pharmacokinetic profile is well‐known in adults, but data in young children are sparse.
Anne Louise de Barros Garioud, Arash Afshari, Lau Romlund Halgreen, Kristian Østergaard Nielsen, Lars Peter Kloster Andersen   +4 more
wiley   +1 more source

Median Effective Volume of 0.2% Ropivacaine for Ultrasound‐Guided Axillary Brachial Plexus Block in Children Aged 6–10 Years: A Prospective Dose‐Finding Study Using Up‐and‐Down Sequential Allocation

Pediatric Discovery, EarlyView.
Purpose: This study aimed to determine the median effective volume (EV50) of 0.2% ropivacaine for ultrasound‐guided axillary brachial plexus block (ABPB) in children aged 6–10 years, using the Dixon up‐and‐down method. The EV50 was 0.350 mL/kg (95% CI: 0.197–0.362 mL/kg), calculated by isotonic regression and bootstrapping.
Tauseef Ahmad, Fei Yang, Yao Xu, Ying Yang, Huanjie Yun, Fei Xu, Yulin Xue, Yu Zhou, Zongke Shi, Yuan Shi, Shangyingying Li, Shengfen Tu   +11 more
wiley   +1 more source

Evidence map and gap analysis of metabolic change in pediatric growth hormone deficiency treated with growth hormone

Pediatric Investigation, EarlyView.
This evidence map of 63 studies (n = 6158) showed growth hormone therapy in children with growth hormone deficiency has neutral glucose effects, mixed lipid outcomes, potential benefits for bone mineral density, bone mineral content, and parathyroid hormone, but generally no impact on thyroid function, body composition, or body mass index.
Wei Wu, Ningyi Song, Yue Zhao, Caiqi Du, Yuning Zhao, You Wu, Xiaoping Luo   +6 more
wiley   +1 more source

Predicting brain age in children aged 2–6 years with autism spectrum disorders using routine T1‐ and T2‐weighted magnetic resonance imaging

Pediatric Investigation, EarlyView.
The routine magnetic resonance imaging‐based model accurately predicted brain age in children aged 2–6. Children with autism spectrum disorder (ASD) exhibited maturational delays at ages 3–5, shifting toward accelerated aging by age 5–6. This exploratory result highlights the dynamic, age‐related developmental heterogeneity in ASD.
Zunying Hu, Rongjia Xiang, Huanyu Luo, Di Hu, Huiying Kang, Huanjie Li, Xin Fan, Yun Peng   +7 more
wiley   +1 more source

Artificial intelligence, equity, and pediatric neurodevelopmental disorders: A scoping review of clinical practice applications

Pediatric Investigation, EarlyView.
Artificial intelligence (AI) is being explored to support diagnosis and care for pediatric neurodevelopmental disorders, yet most tools remain in early stages of development. This scoping review identifies limited external validation, narrow population representation, and sparse equity considerations, underscoring the need for inclusive, clinically ...
Florida Uzoaru, Obinna O. Oleribe, Ucheoma Nwaozuru, Parichart Sabado   +3 more
wiley   +1 more source

Plants, people and their shared heritage: A comparative medicinal and wild food ethnobotany of Albanians, Greeks and Aromanians living in the Gjirokaster area, southern Albania

PLANTS, PEOPLE, PLANET, EarlyView.
Traditional knowledge about wild plants connects people to nature and sustains both cultural identity and biodiversity. This study explores how cultural exchange among Albanians, Greeks and Aromanians in southern Albania shapes the use and naming of medicinal and food plants.
Evanthia Dina, Ani Bajrami, Mousaab Alrhmoun, Naji Sulaiman, Konstantinos Ntinas, Marjol Meço, Bledar Pulaj, Nektarios Aligiannis, Avni Hajdari, Andrea Pieroni   +9 more
wiley   +1 more source

Pseudo‐Dystonic Gait in a Preschool Child: Foot Posturing Contralateral to a Cuboid Fracture

Movement Disorders Clinical Practice, EarlyView.
Allison J. Chirigos, Donald L. Gilbert, Barbara E. Hallinan, Jes Marchbank, Alberto J. Espay   +4 more
wiley   +1 more source