Results 121 to 130 of about 5,939,449 (303)
Big Data and Cognitive ComputingThe International Classification of Diseases (ICD) serves as a widely employed framework for assigning diagnosis codes to electronic health records of patients.
Ilyas Aden +2 more
doaj +1 more source
Summary of Findings from the Child Labor Surveys in the Cocoa Sector of West Africa [PDF]
, 2002 International Child Labor Program - Bureau of International Affairs (ILAB)ChildLaborCocoaFindings.pdf: 1028 downloads, before Oct.
International Child Labor Program, U.S.
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Pathways to Service Receipt: Modeling Parent Help-Seeking for Childhood Mental Health Problems [PDF]
, 2014 Understanding parent appraisals of child behavior problems and parental help-seeking can reduce unmet mental health needs. Research has examined individual contributors to help-seeking and service receipt, but use of structural equation modeling (SEM) is
Mian, Nicholas D.
core +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Aprendizagem contestada em ambiente de mudança radical
RAE: Revista de Administração de Empresas, 2004 Este artigo oferece uma análise da aprendizagem nas organizações em condições de mudança radical, em que a reestruturação da organização foi motivada por uma mudança na ideologia e na propriedade. Discute-se que, nessas circunstâncias, a aprendizagem não
Suzana Braga Rodrigues +2 more
doaj
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source