Results 21 to 30 of about 414,015 (269)

Parental Reports of Stigma Associated with Child’s Disorder of Sex Development

International Journal of Endocrinology, 2015
Disorders of sex development (DSD) are congenital conditions in which chromosomal, gonadal, or anatomic sex development is atypical. DSD-associated stigma is purported to threaten positive psychosocial adaptation. Parental perceptions of DSD-related stigma were assessed in 154 parents of 107 children (newborn–17 years) questionnaire comprising two ...
Aimee M. Rolston, Melissa Gardner, Eric Vilain, David E. Sandberg   +3 more
openaire   +5 more sources

The Influence of Postnatal Psychiatric Disorder on Child Development [PDF]

Psychopathology, 2008
There is considerable evidence that maternal postnatal psychiatric disorder has an adverse influence on infant development. In attempting to examine the pathways of intergenerational transmission, most research has concentrated on genetic factors or on maternal behaviours during mother-child interaction and attachment. However, researchers have largely
Alan Stein, Annukka Lehtonen, Allison G. Harvey, Rosie Nicol-Harper, Michelle Craske   +4 more
openaire   +1 more source

The Relationship between Retinol-Binding Protein 4 and Markers of Inflammation and Thrombogenesis in Children with Kawasaki Disease

Mediators of Inflammation, 2021
Background. Kawasaki disease (KD) is a self-limited vasculitis with unknown etiologies, and coronary artery lesions (CALs) are the most common and serious complications.
Maoling Yang, Haobo Weng, Qiongfei Pei, Fengchuan Jing, Qijian Yi   +4 more
doaj   +1 more source

A new modified Duckett urethroplasty for repair of proximal hypospadias with severe chordee: outcomes of 133 patients

BMC Urology, 2022
Background Despite the continuous development and evolution of surgical methods and techniques, proximal hypospadias remains one of the most challenging issues for pediatric urologists.
Chong Wang, Zhi-Cheng Zhang, De-Ying Zhang, Yi Hua, Feng Liu, Da-Wei He, Guang-Hui Wei, Xing Liu   +7 more
doaj   +1 more source

STAMMERING AS A DISORDER OF SPEECH DEPENDENT ON CONDITIONS OF CHILD DEVELOPMENT [PDF]

Archives of Pediatrics & Adolescent Medicine, 1919
As the facts concerned with child development become collaborated into a more exact and unified body of scientific knowledge, it will become easier to understand tendencies to perversion from the normal that may appear at any point in the child's developmental progress. The ultimate attainment of normality in the adult depends on two great factors: (1)
openaire   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

Alpha-lipoic acid alleviates cognitive deficits in transgenic APP23/PS45 mice through a mitophagy-mediated increase in ADAM10 α-secretase cleavage of APP

Alzheimer’s Research & Therapy
Background Alpha-lipoic acid (ALA) has a neuroprotective effect on neurodegenerative diseases. In the clinic, ALA can improve cognitive impairments in patients with Alzheimer’s disease (AD) and other dementias.
Jie Zhang, Yanshuang Jiang, Xiangjun Dong, Zijun Meng, Liangye Ji, Yu Kang, Mingjing Liu, Weihui Zhou, Weihong Song   +8 more
doaj   +1 more source

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

7,8-dihydroxyflavone ameliorates motor deficits via regulating autophagy in MPTP-induced mouse model of Parkinson’s disease

Cell Death Discovery, 2021
Parkinson’s disease (PD) is a neurodegenerative disease characterized by the loss of dopaminergic neurons in the substantia nigra and diminished dopamine content in the striatum.
Li Zuo, Chunfang Dai, Lilin Yi, Zhifang Dong   +3 more
doaj   +1 more source

Tic disorder developing following risperidone in a child with oppositional defiant disorder [PDF]

Psychiatry and Clinical Psychopharmacology, 2017
Oppositional defiant disorder (ODD), one of the psychiatric disorders frequently encountered in childhood, is a disruptive behaviour disorder involving emotional and behavioural problems. Children with ODD may experience difficulty in controlling anger and are generally disobedient and defiant of other people.
İsmail Akaltun, Tayfun Kara
openaire   +2 more sources