Results 51 to 60 of about 1,304,866 (266)

Global Child Health Is Local Child Health

Journal of Pediatric Health Care, 2022
Julie Marie Buser, Asma A. Taha
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Evolution of pneumococcal serotype 19A in children in Bangladesh: insights from genomic analysis

BMC Microbiology
Background Invasive pneumococcal disease (IPD), caused by Streptococcus pneumoniae, remains a major global health concern, particularly for children.
Arif Mohammad Tanmoy, Esha Kazi, Naito Kanon, Hafizur Rahman, Harry C.H. Hung, Md Hasanuzzaman, Roly Malaker, Apurba Rajib Malaker, Deb Purna Keya, Sudipta Deb Nath, Belal Hossain, Shampa Saha, Mohammad Jamal Uddin, Lesley McGee, Stephen D. Bentley, Stephanie W. Lo, Yogesh Hooda, Samir K. Saha, Senjuti Saha   +18 more
doaj   +1 more source

Verklaringen en aanbevelingen voor de dalende vaccinatiegraad onder kinderen tot twee jaar: impact van de coronapandemie

JGZ
Inleiding:  Steeds minder ouders in Nederland laten hun kinderen tot twee jaar (volledig)  vaccineren. Het vertrouwen in vaccinaties na 2020 in Nederland is niet hersteld, zoals elders in Europa.
Claudia Vrijhof, Lisanne Vonk, Katharina Preuhs, Hilde van Keulen   +3 more
doaj   +1 more source

Epidemiology and risk factors for pneumonia severity and mortality in Bangladeshi children <5 years of age before 10-valent pneumococcal conjugate vaccine introduction

BMC Public Health, 2016
Background Pneumonia is the leading infectious cause of morbidity and mortality in young children in Bangladesh. We present the epidemiology of pneumonia in Bangladeshi children
Shampa Saha, Md Hasan, Lindsay Kim, Jennifer L. Farrar, Belal Hossain, Maksuda Islam, ASM Nawshad Uddin Ahmed, M. Ruhul Amin, Mohammed Hanif, Manzoor Hussain, Shams El-Arifeen, Cynthia G. Whitney, Samir K. Saha   +12 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Diagnostic Accuracy of the Depression Anxiety Stress Scale for Youth (DASS-Y) Indonesian Version for Screening Internalizing Disorders Among Adolescents

Psychology Research and Behavior Management
Andra Kurnianto,1,2 Meita Dhamayanti,1 Rodman Tarigan Girsang,1,3 Eddy Fadlyana,1 Kusnandi Rusmil,1 Mei Neni Sitaresmi,4 Bintang Arroyantri Prananjaya21Department of Child Health, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia; 2Faculty
Kurnianto A, Dhamayanti M, Girsang RT, Fadlyana E, Rusmil K, Sitaresmi MN, Prananjaya BA   +6 more
doaj  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source