Results 71 to 80 of about 1,509,749 (267)
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Published FY 90-FY 93 by the Bureau of Maternal and Child Health; FY 94-FY 96 by Bureau for Children, Youth and ...
Kansas. Bureau of Maternal and Child Health
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Understanding child neglect [PDF]
Child neglect is one of the most common forms of maltreatment. Neglect is a topic that encompasses complex issues, many of which are also emerging research areas. This paper aims to provide a broad overview of these issues in relation to current thinking
Debbie Scott
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Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
First-in-human clinical study of an embryonic stem cell product for urea cycle disorders
Background This study assesses the safety and efficacy of hepatocyte-like cell (HLC) infusion therapy derived from human embryonic stem cells as bridging therapy for neonatal-onset urea cycle disorders (UCD).
Akihiro Umezawa +38 more
doaj +1 more source
Published FY 90-FY 93 by the Bureau of Maternal and Child Health; FY 94-FY 96 by Bureau for Children, Youth and ...
Kansas. Bureau of Maternal and Child Health
core
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Statistical Tables for 1991 Northern Territory Maternal & Child Health Committee
Northern Territory Maternal & Child Health committee Meeting 1991 statistical ...
Maternal and Child Health Committee +3 more
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