Results 241 to 250 of about 1,978,323 (298)

Timing Mechanotransduction: Mechanically Dynamic Biomaterials Reveal the Temporal Hierarchy of YAP/TAZ Control Nodes

Advanced Science, EarlyView.
This work develops dynamically softening polyacrylamide hydrogels for time‐resolved imaging during continuous mechanical transitions. The study revealed that mechanotransduction is biphasic; YAP/TAZ inactivation is driven by early loss of the nucleocytoskeletal continuum connecting subnuclear adhesions, F‐actin, and the nuclear envelope, coupled with ...
Alessandro Gandin, Giada Vanni, Veronica Torresan, Margherita Pelosin, Rebecca Busetto, Anna Citron, Ambela Suli, Paolo Contessotto, Carlo Albanese, Francesca Zanconato, Tito Panciera, Stefano Piccolo, Giovanna Brusatin   +12 more
wiley   +1 more source

'Better Conversations With Developmental Language Disorder': Designing a Novel Intervention for School-Aged Children and Their Main Carers. [PDF]

Int J Lang Commun Disord
Hughes L, Croot L, Newton C, Best W.
europepmc   +1 more source

De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning

Advanced Science, EarlyView.
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li, Haifan Gong, Yue Wang, Yinuo Zhao, Lixiang Li, Peijing Bao, Qingzhou Kong, Jialu Fu, Boyao Wan, Yumeng Zhang, Jinghui Zhang, Jiekun Ni, Zhongxue Han, Xueping Nan, Kunping Ju, Longfei Sun, Yuerui Ma, Huijun Chang, Mengqi Zheng, Yanbo Yu, Xiaoyun Yang, Xiuli Zuo, Haina Wang, Yanqing Li   +23 more
wiley   +1 more source

"Disconnected From Everyone and Everything Around Them": A Mixed Method Study to Explore the Perspectives of Children With Language Difficulties and Their Caregivers On Mental Health Concerns and Mental Health Support. [PDF]

Int J Lang Commun Disord
Wilmot A, Boyes M, Kippin N, Van Heerden D, Jones K, Leitão S, Jackson E, Tonta K, Myers B, Hill E.   +9 more
europepmc   +1 more source

Solid Harmonic Wavelet Bispectrum for Image Analysis

Advanced Science, EarlyView.
The Solid Harmonic Wavelet Bispectrum (SHWB), a rotation‐ and translation‐invariant descriptor that captures higher‐order (phase) correlations in signals, is introduced. Combining wavelet scattering, bispectral analysis, and group theory, SHWB achieves interpretable, data‐efficient representations and demonstrates competitive performance across texture,
Alex Brown, Mathilda Avirett‐Mackenzie, Carolin Villforth, Georgios Exarchakis   +3 more
wiley   +1 more source

A Customised, Intensive Parent-Child Interaction Therapy for Children With Down Syndrome: Findings From a Real-World Pilot Effectiveness Study. [PDF]

Int J Lang Commun Disord
O'Toole C, Moloney H, McCarthy C, Vousden S, O'Sullivan A, Flynn D, Stokes S, Quinn ED, Frizelle P.   +8 more
europepmc   +1 more source

Speech language pathologists' attitudes on bilingual practices for children with autism in India: A qualitative study. [PDF]

PLoS One
Sree KB, Padickaparambil S, Tiwari S.
europepmc   +1 more source

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Child-Language Corpora

2020
Together with experiments, the main method in the study of child language development is the analysis of behavioral changes of individual children over time. For this purpose recordings of infants’ and children’s naturalistic interactions in a variety of languages spoken in different cultural contexts are key.
Stoll, Sabine, Schikowski, Robert
openaire   +1 more source

Child Language Acquisition

2011
Is children's language acquisition based on innate linguistic structures or built from cognitive and communicative skills? This book summarises the major theoretical debates in all of the core domains of child language acquisition research (phonology, word-learning, inflectional morphology, syntax and binding) and includes a complete introduction to ...
Ambridge, Ben, Lieven, Elena V.M.
openaire   +4 more sources

Child Language

2007
Abstract This is a systematic presentation of the parametric approach to child language. Linguistic theory seeks to specify the range of grammars permitted by the human language faculty and thereby to specify the child's "hypothesis space" during language acquisition. Theories of language variation have central implications for the study
openaire   +1 more source