Results 81 to 90 of about 1,978,323 (298)

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Two negations for the price of one

open access: yesGlossa, 2016
Standard English is typically described as a double negation language. In double negation ­languages, each negative marker contributes independent semantic force. Two negations in the same clause usually cancel each other out, resulting in an affirmative
Anna Notley   +3 more
doaj   +2 more sources

Cognate facilitation effects in bilingual children of varying language dominance [PDF]

open access: yes, 2018
A widely accepted theory is that bilinguals activate both of their languages regardless of which is in use. Though there is abundant research on this phenomenon in bilingual adults, less research has focused on bilingual children.
Ramirez, Mayra Chantal
core   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

The Arizona Kith and Kin Project Evaluation, Brief #3 [PDF]

open access: yes, 2016
Professional Development with Family, Friend, and Neighbor Providers: Implications for Dual Language Learners. Indigo Cultural Center, for the Association for Supportive Child Care, with support from First Things First and Valley of the Sun United ...
Farago, Flora   +2 more
core   +1 more source

What's in a name? Coming to terms with the child's linguistic environment [PDF]

open access: yes, 2008
This article reviews the proliferation of terms that have been coined to denote the language environment of the young child. It is argued that terms are often deployed by researchers without due consideration of their appropriateness for particular ...
Saxton, Matthew
core   +2 more sources

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela   +13 more
wiley   +1 more source

The effect of child labor on mathematics and language achievement in Latin America [PDF]

open access: yes
The authors use a unique data set on language, and mathematics test scores for third, and fourth graders in eleven different Latin American countries, to determine whether child labor raises or lowers school achievement.
Gunnarsson, Victoria   +2 more
core  

Prenatal exposure to methadone or buprenorphine: Early childhood developmental outcomes. [PDF]

open access: yes, 2018
BACKGROUND: Methadone and buprenorphine are recommended to treat opioid use disorders during pregnancy. However, the literature on the relationship between longer-term effects of prenatal exposure to these medications and childhood development is both ...
Coyle, Mara G.   +8 more
core   +1 more source

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte   +13 more
wiley   +1 more source

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