Results 71 to 80 of about 314,616 (264)

Crianças com implante coclear: habilidades comunicativas e qualidade de vida Children with cochlear implants: communication skills and quality of life

Brazilian Journal of Otorhinolaryngology, 2012
Dado o âmbito multidimensional do implante coclear, há crescente necessidade em avaliar não somente medidas clínicas de eficácia relacionadas às habilidades comunicativas, mas também aspectos mais genéricos envolvidos na efetividade do tratamento, como a
Talita Fortunato-Tavares, Debora Befi-Lopes, Ricardo Ferreira Bento, Claudia Regina Furquim de Andrade   +3 more
doaj   +1 more source

On Hierarchical Composite Endpoints in Pediatric Cancer Supportive Care: Illustrative Examples From Two Multi‐Center Phase‐III Randomized Clinical Trials

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier, Mark Zobeck, Adam J. Esbenshade, Christopher C. Dvorak, Lillian Sung, David Freyer, Sarah Alexander, Etan Orgel, Nicole J. Ullrich, Zach Prudowsky, Brian Fisher, Caitlin W. Elgarten   +11 more
wiley   +1 more source

Usos de porque en el habla infantil: Implicaciones del desarrollo de la complejidad sintáctica1 [PDF]

Sintagma, 2019
The acquisition and development of complex sentences in child language is a topic of growing interest within specialized literature for its theoretical and practical implications.
Iván Enríquez Martínez
doaj  

Eesti lastekeele korpuse morfoloogilise märgendamise kitsaskohtadest

Eesti Rakenduslingvistika Ühingu Aastaraamat, 2017
"Issues in morphological annotation of the Estonian child language corpus" This article presents the results of an initial attempt to automatically annotate the currently existing, publicly available Estonian child language corpus morphologically ...
Kristiina Vaik, Virve-Anneli Vihman
doaj   +1 more source

Determining Parental Factors for Clinical Trial Attrition in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Despite high enrollment rates on Children's Oncology Group (COG) protocols, attrition after initial consent is challenging, introducing bias and prolonging trial completion. While adult oncology literature has identified predictors of withdrawal, little is known about caregiver decision‐making for child participation in ...
Kimberly L. Stathas, Jakob Q. Weiss, Kellee N. Parker, Cathy Lee‐Miller   +3 more
wiley   +1 more source

Impact of Japan's 2024 Physician Work‐Style Reform on Pediatric Hematology–Oncology: Educational Implications in a 2‐Year Survey

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Japan's 2024 physician work‐style reform introduced legally binding limits on physicians’ working hours, but its impact on education and workforce sustainability in pediatric hematology–oncology (PHO) remains unclear. Procedure We conducted a repeated cross‐sectional study with structured quantitative items and free‐text responses ...
Kiyohiko Kaizu, Masaharu Akiyama, Toshikazu Itabashi, Jun Hayakawa, Takahiro Kikuchi, Ryohei Fukunaga, Katsuyoshi Koh, Takahiro Ueda   +7 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

The Development of Questions in Child and Child-directed Speech in Turkish

Dilbilim Araştırmaları Dergisi
Child-directed questions are significant in high-quality mother-child interactions (Ninio, 1980; Rowe, Leech & Cabrera., 2017). This paper examines the probable effects of Turkish child-directed speech (CDS) on the acquisition of wh-words of a Turkish ...
Vildan İnci KAVAK
doaj   +1 more source

Küsimuste sõnajärje mõju nähtud isiku mäletamise täpsusele 4- ja 6-aastastel eesti lastel

Eesti Rakenduslingvistika Ühingu Aastaraamat, 2016
"The effect of word order in questions to the recall accuracy of a person of 4- and 6-years-old Estonian children" It is important to interview a child witness or victim in the criminal justice system in such a way that the information retrieved from ...
Kristjan Kask, Reili Argus, Kristel Veerus   +2 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source