Results 31 to 40 of about 646,168 (259)

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Increased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters, Ji Yun Tark, Tiffany M. Chambers, Tania A. Desrosiers, Michael E. Scheurer, Charles Shumate, Wendy N. Nembhard, Mahsa M. Yazdy, Eirini Nestoridi, Amanda E. Janitz, Jean Paul Tanner, Russell S. Kirby, Jason L. Salemi, Yao Yu, Chad D. Huff, Sharon E. Plon, Philip J. Lupo, Jeremy M. Schraw   +17 more
wiley   +1 more source

An Analysis of the Educational Perspective of Hidayet Karakuş in His Works Within the Framework of Child Literature

Anadolu Üniversitesi Eğitim Fakültesi dergisi, 2018
The negativities in our children's cognitive, emotional and mental development, or their failure to attain the essential values ​​they need to earn, will bring our existence to the point of ending our existence.
Kadir Kaplan, Mahmut Babacan
doaj  

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Hidayet Karakuş’un Çocuk Edebiyatı Çerçevesinde Yazdığı Eserlerinde Eğitime Bakış Açısının Analizi

Anadolu Üniversitesi Eğitim Fakültesi dergisi, 2018
Çocuklarımızın bilişsel, duyuşsal, zihinselgelişiminde yaşanacak olumsuzluklar ya da kazanmaları gereken temel değerlerikazanamamaları geleceğimizi yok etme, varlığımızı bitirme noktasınagetirecektir.
Mahmut Babacan, Kadir Kaplan
doaj  

Child Malnutrition in Pakistan: Evidence from Literature

Children, 2018
Pakistan has one of the highest prevalences of child malnutrition as compared to other developing countries. This narrative review was accomplished to examine the published empirical literature on children’s nutritional status in Pakistan.
Muhammad Asim, Yasir Nawaz
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Türkçe Öğretmeni Adaylarının Çocuk Edebiyatı Dersine İlişkin Düşünceleri Üzerine Olgubilimsel Bir Araştırma

Sakarya Üniversitesi Eğitim Fakültesi Dergisi, 2016
Çalışma Türkçe öğretmeni adaylarının çocuk edebiyatı dersine ilişkin tecrübelerini paylaşmak amacıyla yapılmış olgubilimsel bir araştırmadır. Erzincan Üniversitesinde yapılan çalışmanın örneklemini, ilgili üniversitenin Türkçe Eğitimi Bölümünde okuyan ...
Oğuzhan Yılmaz
doaj  

Interactions between autistics and healthy children and their parents in emotional availability: a comparative study

Cambridge Prisms: Global Mental Health
In this study, we assessed the interactions of mothers and fathers with their children diagnosed with autism spectrum disorder (ASD) in terms of emotional availability (EA) and compared them with the interactions of healthy controls. Children, aged 13–60 
Belgin Ustun Gullu, Didem Behice Oztop, Eda Umutlu Aydin, Baris Ors, Merve Cikili Uytun, Esra Yurumez   +5 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source