Results 51 to 60 of about 646,168 (259)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Humanus: Jurnal Ilmiah Ilmu-ilmu Humaniora, 2014 Child-created children’s literature that grown in Indonesia in 2000s, particular-ly those about family, tends to describe women as mothers. This is because the young writers still live with their mothers that the nurturing habits of the mother are ...
Yenni Hayati
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
PSYCHOPATHIC PERSONALITY DISORDER IN LARSSON’S “THE GIRL WITH THE DRAGON TATTOO”
Lire Journal, 2020 This paper investigates how childhood trauma causes someone to suffer from a personality disorder. The narrative discussed in this paper is The Girl with the Dragon Tattoo by Stieg Larsson (2005). The main character of the story, Martin Vanger, is unable
Christy Tisnawijaya, Puji Astuti
doaj +1 more source
The literature on child abuse fatalities: a bibliography [PDF]
Child Abuse Review, 1995 The best starting places for examining the literature on child abuse fatalities are special issues of child abuse journals. These are this issue of Child Abuse Review, a special issue of the APSAC Advisor, published by the American Professional Society on the Abuse of Children, and the ‘Spotlight on Practice’ section of an issue of Child Abuse and ...
openaire +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The vocabulary of Yiddish-Hebrew speaking children – A CDI study
AmpersandYiddish-Hebrew speakers residing in Israel are primarily Ashkenazi ultra-Orthodox Jews, living in relatively closed communities, characterized by their large number of children, low parental formal education, and low family income. Religious literacy and
Odelya Ohana +2 more
doaj +1 more source
Intercostal leiomyoma in a child: review of the literature
Pan African Medical Journal, 2017 Leiomyomas of the chest wall are very rare. In a review of the current literature twelve cases were found, of which only one concerns of an intercostal leiomyoma of the chest wall. We report a case of 1 year old male child with intercostal leiomyoma who presented with a painless rigid swelling of the right chest wall.
Kleanthis Anastasiadis +4 more
openaire +4 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source