Results 31 to 40 of about 4,554,350 (295)
U.S. Environmental Protection Agency Regional Laboratory Network: Annual Report 2014 [PDF]
, 2015 This report discusses the Environmental Protection Agency Regional Laboratories that are state-of-the-art, full-service environmental laboratories that deliver analytical services, field support, and data review.
United States. Environmental Protection Agency.
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Child Fostering or Child Trafficking: Questioning Justifications for Children’s Departure from Home
Indonesian Journal of Social and Environmental Issues, 2021 West African countries adopt child fostering or kinship placement as a traditional form of social protection that balances care and support for families with limited resources, experiencing unforeseen setbacks; or requiring household support.
Ifeyinwa Mbakogu
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Unes Journal of Swara Justisia, 2019 Investigation of criminal cases committed by children by police investigators in accordance with Law Number 8 of 1981 concerning Criminal Procedure Law (KUHAP) and Law Number 11 of 2012 concerning the Child Criminal Justice System.
Edi Karan Prianto, Otong Rosadi
doaj
Religions, 2022 Since the emergence of the #MeToo and #ChurchToo movements, online tracts have been employed to publicly reveal experiences of sexual abuse and assault among women and men in religious institutions and to shame abusers, which tend to be examined as an ...
Ben Kasstan
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Critical Debates and Developments in Child Protection [PDF]
, 2020 This book includes chapters from a range of countries which critically reflect on recent developments in child protection policy and practice. It is a follow-up to ‘Contemporary Developments in Child Protection’ Volumes 1, 2 and 3, which were published ...
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RCPCH: Child protection standing committee update November 2023
, 2023 Our knowledgeChanges to consent guidance for Child Protection medicals: We have strengthened our guidance on obtaining consent for Child Protection medicals. This will be uploaded to the child protection companion shortly.
Fussey, Elizabeth +2 more
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source