Results 51 to 60 of about 4,554,350 (295)

Contact with child protection services during pregnancy: a cross-sectional study using the eLIXIR Born in South London, UK maternity-child data linkage

BMC Pregnancy and Childbirth
Background In the last decade, rates of children with child protection agency involvement have increased in many high-income countries, including the UK.
Kaat De Backer, Paul Seed, Sam Burton, Elsa Montgomery, Jane Sandall, eLIXIR-Born in South London Partnership, Abigail Easter   +6 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Humanity and Resilience: child-friendly spaces in Syria’s protracted conflict [PDF]

População e Sociedade
This paper seeks to analyse how education and child-friendly spaces impact the resilience of Syrian children affected by the protracted conflict, by ensuring humanity, dignity and protection.
Ariane Medeiros da Costa, Joana Macedo Rocha   +1 more
doaj   +1 more source

Child protection Australia 2013–14 [PDF]

, 2015
Contains comprehensive information on state and territory child protection and support services in 2013-14, and the characteristics of Australian children within the child protection system.
Australian Institute of Health and Welfare
core  

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Child Protection and Social Inequality: Understanding Child Prostitution in Malawi

Social Sciences, 2018
This article draws on empirical research to develop understandings of child prostitution, previously theorised on the basis of children’s rights, feminist, and structure/agency debates, largely ignoring children’s own understandings of their ...
Pearson Nkhoma, Helen Charnley
doaj   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Shifting Power at the Front Door: State–Community Decision-Making Partnerships in Child Protection

Social Sciences
Inequities for Indigenous people in child protection systems are well established. One avenue for addressing these inequities is at the ‘front door’ of child protection, when reports are first made to statutory child protection services.
Emily Keddell, Andrew Rudolph, Shayne Walker, Karen Hale, Jude Hughes, Jonette Chapman, William Kaipo   +6 more
doaj   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

Famílias e violência doméstica: condições psicossociais pós ações do conselho tutelar

Psicologia: Ciência e Profissão
O texto aborda as condições familiares implicadas em situações de risco psicossocial, focalizando o problema da violência doméstica e suas repercussões no desenvolvimento psicossocial de crianças.
Rute Grossi Milani, Sonia Regina Loureiro   +1 more
doaj   +3 more sources