Results 41 to 50 of about 4,554,350 (295)

Measuring the immeasurable: Understanding the effectiveness of anti-child trafficking transnational advocacy networks

Cosmopolitan Civil Societies: An Interdisciplinary Journal, 2013
Transnational advocacy networks’ anti-child trafficking efforts have led to significant progress in the Mekong Subregion by bringing the child trafficking issue onto the global social policy agenda, resulting in new child protection legislation and ...
Deanna Davy
doaj   +1 more source

Child Protection and Safeguarding in England: Changing and Competing Conceptions of Risk and their Implications for Social Work [PDF]

, 2010
This paper critically reflects on policy developments and debates in England in relation to child protection and safeguarding over the past twenty years.
N. Parton, Parton, Nigel
core   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Feasibility of a Healthy Relationships Program with Youth at a Child Protective Services Agency

Child and Adolescent Social Work Journal, 2022
AbstractYouth involved in child welfare may benefit from programming that enhances their relationship skills given their susceptibility to engaging in high-risk interpersonal behaviors that can lead to challenges such as, engaging in or experiencing violence, housing and job insecurity, and poor physical and mental health.
Bridget Houston, Claire Crooks
openaire   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

The link between hearing impairment and child maltreatment among Aboriginal children in the Northern Territory of Australia: is there an opportunity for a public health approach in child protection?

BMC Public Health, 2020
Background International studies provide evidence of an association between child disabilities, including hearing impairment (HI), and child maltreatment.
Vincent Yaofeng He, Steven Guthridge, Jiunn-Yih Su, Damien Howard, Kylie Stothers, Amanda Leach   +5 more
doaj   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Child advocacy centers: Perspectives from frontline child protection workers in Michigan, USA

Child Protection and Practice
Providing a coordinated response to child abuse among professionals from diverse fields has the potential to improve outcomes for children and advance justice in abuse cases. The multidisciplinary team model, implemented through child advocacy centers in
Nathyn A. Thompson, Kaylee R. Bares, Sarah R. Carlson   +2 more
doaj   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source