Results 41 to 50 of about 58,566 (300)
Religions, 2022 Since the emergence of the #MeToo and #ChurchToo movements, online tracts have been employed to publicly reveal experiences of sexual abuse and assault among women and men in religious institutions and to shame abusers, which tend to be examined as an ...
Ben Kasstan
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Understanding child neglect [PDF]
, 2014 Child neglect is one of the most common forms of maltreatment. Neglect is a topic that encompasses complex issues, many of which are also emerging research areas. This paper aims to provide a broad overview of these issues in relation to current thinking
Debbie Scott
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Unes Journal of Swara Justisia, 2019 Investigation of criminal cases committed by children by police investigators in accordance with Law Number 8 of 1981 concerning Criminal Procedure Law (KUHAP) and Law Number 11 of 2012 concerning the Child Criminal Justice System.
Edi Karan Prianto, Otong Rosadi
doaj
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Child Trafficking in Glasgow: Report of a Social Work Case File Analysis of Unaccompanied Asylum Seeking Children [PDF]
, 2009 This research is the first phase of work in Glasgow to explore the prevalence of child trafficking in the city and to establish a knowledge base about children who may have been trafficked. A sample group of 75 unaccompanied asylum seeking children (UASC)
Rigby, Paul
core
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Cosmopolitan Civil Societies: An Interdisciplinary Journal, 2013 Transnational advocacy networks’ anti-child trafficking efforts have led to significant progress in the Mekong Subregion by bringing the child trafficking issue onto the global social policy agenda, resulting in new child protection legislation and ...
Deanna Davy
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source