Results 131 to 140 of about 1,598,227 (311)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Global norms, organizational action: Leveraging international children’s rights law to advance child safeguarding

open access: yesLeiden Journal of International Law
Tragically, the abuse of children within organizational contexts continues to persist across time and geographies. Various institutions established for children’s care and protection have repeatedly been exposed as epicentres of abuse.
Afrooz Kaviani Johnson
doaj   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

open access: yesFEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart   +4 more
wiley   +1 more source

Is there a place for work in child development? Implications of child development theory and research for interpretation of the UN Convention on the Rights of the Child, with particular reference to Article 32, on children, work and exploitation [PDF]

open access: yes, 1999
This paper is about the role of child-development knowledge and research in international efforts to improve the lives and prospects for millions of working children.
Woodhead, Martin
core  

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

Rights and situation of childhood in the framework of the Declaration of Human Rights

open access: yesMiscelánea Comillas, 2013
This paper reviews the development of children’s rights since the Universal Declaration of Human Rights. We will focus on the Declaration of the Rights of the Child (1959) and the Convention on the Rights of the Child (1989) because they are the two ...
Jorge Uroz Olivares
doaj  

Afirmacja praw dziecka a jego obowiązki wobec rodziny

open access: yesKrytyka Prawa
Everyone’s personal dignity guarantees freedoms and rights irrespective of age, which means that they also apply to the child. The rights of the child emphasise his or her subjectivity and draw attention to his or her special status determined ...
Wojciech Lis
doaj   +1 more source

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