Results 131 to 140 of about 1,891,659 (347)

Dynamic mapping of human cortical development during childhood through early adulthood.

Proceedings of the National Academy of Sciences of the United States of America, 2004
B. Perry, M. White, S. Dorman, Gogtay Md, J. Giedd, Leslie Lusk Ba, Kiralee M Hayashi Bs, D. Greenstein, A. Vaituzis, David H Herman Bs, Thomas F. Nugent, Iii Ab, L. Clasen, A. Toga, J. Rapoport, P. Thompson, J. Sb, Blum Rw, T. H, Lenroot Rk, Greenstein Dk, T. L., Pierson R Giedd, Jn Cerebellum, Giedd Jn, Lalonde Fm, Celano Mj, White Sl, Wallace Gl, Lee Nr, Lenroot Rk Anatomical Brain Magnetic, S. P, A. A, E. a, R. J   +34 more
semanticscholar   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Childhood-onset lupus nephritis: long-term outcomes and their predictors [PDF]

Eugene Yu-hin Chan, Chiara De Mutiis, Kjell Tullus   +2 more
openalex   +1 more source

A gradient of childhood self-control predicts health, wealth, and public safety

Proceedings of the National Academy of Sciences of the United States of America, 2011
T. Moffitt, L. Arseneault, Daniel W Belsky, N. Dickson, R. Hancox, H. Harrington, R. Houts, R. Poulton, B. Roberts, Stephen Ross, M. Sears, W. Murray Thomson, A. Caspi, J. Heckman, Heck Jj, Malofeeva L Pinto   +15 more
semanticscholar   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Maternal distress, parenting stress, maladaptive parenting and children’s problematic media use in China: evidence from 2022 spring in Shanghai

BMC Public Health
The COVID-19 lockdown has forced young children to spend more time on media and significantly impacted their mothers’ mental health. This study explored how mothers’ individual distress influences children’s problematic media use during the Shanghai ...
Jingyao Wang, Shumin Wang, Bowen Xiao, Juan Li, Yuemin Feng, Yan Li   +5 more
doaj   +1 more source

Dose response association of pregnancy cigarette smoke exposure, childhood stature, overweight and obesity [PDF]

, 2010
Gibby Koshy, Ali Delpisheh, Bernard J. Brabin   +2 more
openalex   +1 more source

Pop Culture and New Media Impact of Internet Use in Parenting on Early Childhood Development

, 2023
Nur Hamzah, Bayu Suratman
openalex   +2 more sources

Childhood epilepsy. [PDF]

BMJ, 1978
openaire   +2 more sources