Results 61 to 70 of about 3,162,749 (346)

Metabolic profile of leukemia cells influences treatment efficacy of L-asparaginase

BMC Cancer, 2020
Background Effectiveness of L-asparaginase administration in acute lymphoblastic leukemia treatment is mirrored in the overall outcome of patients.
Katerina Hlozkova, Alena Pecinova, Natividad Alquezar-Artieda, David Pajuelo-Reguera, Marketa Simcikova, Lenka Hovorkova, Katerina Rejlova, Marketa Zaliova, Tomas Mracek, Alexandra Kolenova, Jan Stary, Jan Trka, Julia Starkova   +12 more
doaj   +1 more source

Effective Early Childhood Programmes [PDF]

, 2009
Published in collaboration with the Open University, Early Childhood in Focus offers accessible and clear reviews of the best and most recent available research, information and analysis on key policy issues, offering clear messages on core policy topics
Siraj-Blatchford, Iram, Woodhead, Martin
core  

Lifestyle Behaviors and Cardiotoxic Treatment Risks in Adult Childhood Cancer Survivors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Higher doses of anthracyclines and heart‐relevant radiotherapy increase cardiovascular disease (CVD) risk. This study assessed CVD and CVD risk factors among adult childhood cancer survivors (CCSs) across cardiotoxic treatment risk groups and examined associations between lifestyle behaviors and treatment risks.
Ruijie Li, Raquel Revuelta Iniesta, Alan R. Barker, Dimitris Vlachopoulos, Tomáš Sláma, Christina Schindera, Fabiën N. Belle   +6 more
wiley   +1 more source

Plasma lipopolysaccharide levels predict mortality in acutely ill children in Low- and Middle-Income Countries

Nature Communications
Childhood mortality remains high in low-resource settings, where environmental enteric dysfunction (EED) is prevalent. Peripheral blood bacterial lipopolysaccharides (LPS) are potential biomarkers of intestinal microbial translocation and inflammation ...
Chris A. D. Allen, Arya Ghate, James M. Njunge, Lisa Gartner, Abdoulaye Hama Diallo, Christina Lancioni, Ezekiel Mupere, Agnes Gwela, Caroline Tigoi, Benson O. Singa, Wilson Gumbi, Robert H. J. Bandsma, Wieger P. Voskuijl, Mohammod Jobayer Chisti, Tahmeed Ahmed, Abu Sadat Mohammad Sayeem Bin Shahid, Dilruba Ahmed, Ali Saleem, Zaubina Kazi, Kelsey Jones, Kirkby D. Tickell, Judd L. Walson, James A. Berkley, Holm H. Uhlig   +23 more
doaj   +1 more source

Cerebrospinal Fluid Liquid Biopsy Enables Targeted Therapy Without Tissue Diagnosis in Pediatric Low‐Grade Gliomas With BRAF V600E Mutation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We present two pediatric cases of pediatric low‐grade gliomas (PLGG) with BRAF V600E mutations diagnosed and monitored using cerebrospinal fluid (CSF) liquid biopsy analyzed via digital droplet PCR (ddPCR), without tissue biopsy. Both patients were treated with dabrafenib and trametinib and monitored through clinical assessments, magnetic ...
Hannah Sultan, Damien Faury, Alexander G. Weil, Harrison J. Westwick, Nada Jabado, Sébastien Perreault   +5 more
wiley   +1 more source

Pathogenesis of formation of frequent respiratory infections in children with Epstein-Barr virus and cytomegalovirus infection

Журнал инфектологии, 2014
The goal was to clarify the pathogenesis of the formation of frequent respiratory infections in children with Epstein-Barr virus and cytomegalovirus infection on the basis of studying the microbial landscape of anti-infective and mucous membranes of the ...
I. V. Babachenko, A. S. Kvetnaya, O. V. Melnik, A. S. Levina   +3 more
doaj   +1 more source

BMI-For-Age Cut-Off as an Indicator of Adiposity among In-School Children (Age 4-11 Years) in Obio/Akpor LGA, Rivers State, Nigeria [PDF]

, 2017
Background: Childhood overweight and obesity has been an issue of great concern to developing and developed nation where as degenerative underweight has ravaged the underdeveloped and war turn countries.
Aigbogun EO Jr, Ibeachu PC, Ikechukwu E
core   +1 more source

Changes in Body Composition in Children and Young People Undergoing Treatment for Acute Lymphoblastic Leukemia: A Systematic Review and Meta‐Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed, Raquel Revuelta Iniesta, Mary Fewtrell, Julie Lanigan, Breeana Gardiner, Graeme O'Connor   +5 more
wiley   +1 more source

A scoping review on early childhood caries and inequalities using the Sustainable Development Goal 10 framework

BMC Oral Health
Background Social inequalities contribute to health disparities. This study aimed to map evidence on early childhood caries (ECC) related to the United Nations' Sustainable Development Goal 10 (SDG 10).
Morẹ́nikẹ́ Oluwátóyìn Foláyan, Elisa Maria Rosa de Barros Coelho, Carlos Alberto Feldens, Balgis Gaffar, Jorma I. Virtanen, Olunike Rebecca Abodunrin, Duangporn Duangthip, Ola B. Al-Batayneh, Ana Vukovic, Maha El Tantawi, Robert J. Schroth   +10 more
doaj   +1 more source

Childhood IQ and marriage by mid-life: the Scottish Mental Survey 1932 and the Midspan Studies [PDF]

, 2005
The study examined the influence of IQ at age 11 years on marital status by mid-adulthood. The combined databases of the Scottish Mental Survey 1932 and the Midspan studies provided data from 883 subjects.
Ben-Shlomo, Buss, Carole L. Hart, Clark, Davey Smith, Davey Smith, David J. Hole, Ellis, Emslie, Frankel, George Davey Smith, Goldman, Gove, Hart, Hawthorne, Herrnstein, Ian J. Deary, Kenrick, Lawrence J. Whalley, Macintyre, Marmot, Michelle D. Taylor, Miller, Modin, Neisser, Valerie Wilson, Vågerö, Whalley   +27 more
core   +1 more source