Results 61 to 70 of about 1,607,316 (314)

Scoping review on the link between economic growth, decent work, and early childhood caries

BMC Oral Health
Background Early Childhood Caries (ECC) is a prevalent chronic non-communicable disease that affects millions of young children globally, with profound implications for their well-being and oral health.
Morẹ́nikẹ́ Oluwátóyìn Foláyan, Rosa Amalia, Arthur Kemoli, Imen Ayouni, Arthemon Nguweneza, Duangporn Duangthip, Ivy Guofang Sun, Jorma I. Virtanen, Ray M. Masumo, Ana Vukovic, Ola B. Al-Batayneh, Balgis Gaffar, Tshepiso Mfolo, Robert J. Schroth, Maha El Tantawi   +14 more
doaj   +1 more source

Queerying' gender : heteronormativity in early childhood education

, 2005
This paper explores heteronormativity and argues for the 'queerying' of gender in early childhood education. The author argues, utilising Butler's theory of performativity and heterosexual matrix, that the construction of gender in young children's lives
Robinson, Kerry H.
core  

Early childhood portfolios as a tool for enhancing learning during the transition to school [PDF]

, 2009
From 2005-2008 Mangere Bridge Kindergarten in New Zealand carried out a Centre of Innovation research project exploring the transition between early childhood education and school.
Peters, Sally, Carr, Margaret, Rogers, Pat, Smith, Jemma, Hartley, Carol   +4 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Plasma lipopolysaccharide levels predict mortality in acutely ill children in Low- and Middle-Income Countries

Nature Communications
Childhood mortality remains high in low-resource settings, where environmental enteric dysfunction (EED) is prevalent. Peripheral blood bacterial lipopolysaccharides (LPS) are potential biomarkers of intestinal microbial translocation and inflammation ...
Chris A. D. Allen, Arya Ghate, James M. Njunge, Lisa Gartner, Abdoulaye Hama Diallo, Christina Lancioni, Ezekiel Mupere, Agnes Gwela, Caroline Tigoi, Benson O. Singa, Wilson Gumbi, Robert H. J. Bandsma, Wieger P. Voskuijl, Mohammod Jobayer Chisti, Tahmeed Ahmed, Abu Sadat Mohammad Sayeem Bin Shahid, Dilruba Ahmed, Ali Saleem, Zaubina Kazi, Kelsey Jones, Kirkby D. Tickell, Judd L. Walson, James A. Berkley, Holm H. Uhlig   +23 more
doaj   +1 more source

Children's leadership strategies in early childhood

, 2011
Young children's leadership is an undertheorized and underresearched topic. Much of the research literature involves paired children working on adult-set tasks that are aimed to provide data on specific aspects of children's collaborative work.
Mawson, William
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Early Childhood Education as Sites for Children’s Citizenship: Tensions, challenges and possibilities in New Zealand’s policy framing [PDF]

, 2010
This paper draws on recent research to examine the tensions and challenges inherent in the current market approach to provision of Early Childhood Care and Education (ECCE) services in Aotearoa New Zealand.
Mitchell, Linda, Davison, Claire
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Meeting the needs of children with congenital and developmental cataract in Africa

Community Eye Health Journal, 2008
In much of Africa, childhood cataract is becoming one of the leading causes of new cases of blindness reported per year.Although there is insufficient data on childhood cataract, both congenital and developmental, the backlog of children in need of ...
Paul Courtright, Childhood Cataract Experts Meeting Group   +1 more
doaj