Results 101 to 110 of about 1,752,397 (306)

Influence of Molecular Genetic Classes on Behavior in Prader‐Willi Syndrome

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT A wide range of behavioral phenotypes has been described in PWS patients including autism spectrum disorder (ASD). The prevalence of behavioral disorders was studied in 292 participants over 3 years with genetically confirmed PWS (N = 164 females and N = 128 males) with deletion (N = 182) and mUPD (maternal uniparental disomy) (N = 99).
Ranim Mahmoud, Merlin G. Butler, Wai Park, Jennifer L. Miller, Daniel J. Driscoll, June‐Anne Gold, Virginia Kimonis   +6 more
wiley   +1 more source

The EXPLAIN Study: Exploring Arthrogryposis Multiplex Congenita in Adults in Norway — A Description of Demographic, Medical, and Neurological Findings

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Arthrogryposis Multiplex Congenita (AMC) encompasses several hundred conditions with diverse genetic, pathophysiological, and clinical origins. The overarching EXPLAIN study explores underlying causes and implications of AMC and represents the largest clinical cohort of adults with AMC reported to date.
My Vuong Hermansen, Kristin Ørstavik, Unni Steen, Mathias Toft, Cathrine Brunborg, Lena Lande Wekre   +5 more
wiley   +1 more source

To What Extent Do Australian Government Metrics Align With Indigenous and Non‐Indigenous Conceptualisations of Wellbeing? A Scoping Review of Wellbeing Frameworks

Australian Journal of Social Issues, EarlyView.
ABSTRACT Indigenous wellbeing theories offer potential to better measure social and cultural determinants. This scoping review aimed to identify the types of metrics used by the Australian government to assess wellbeing and evaluate the alignment of current frameworks against Indigenous and non‐Indigenous conceptualisations of wellbeing.
Sophie Wright‐Pedersen, Edward J. O'Connor, Megan Rebuli, Tiana Thorne, Naomi Kakoschke, Ray Mahoney   +5 more
wiley   +1 more source

Childhood Obesity, Cortical Structure, and Executive Function in Healthy Children

Cerebral Cortex, 2019
The development of executive function is linked to maturation of prefrontal cortex (PFC) in childhood. Childhood obesity has been associated with changes in brain structure, particularly in PFC, as well as deficits in executive functions.
L. Ronan, Aaron F. Alexander-Bloch, P. Fletcher   +2 more
semanticscholar   +1 more source

Growth Differentiation Factor 15 as a Cerebrospinal Fluid Biomarker for the Diagnosis and Prognosis of Leptomeningeal Metastasis

Annals of Neurology, EarlyView.
Objective As leptomeningeal metastasis (LM) has a poor prognosis, reliable cerebrospinal fluid (CSF) diagnostic biomarkers are urgently needed. This study evaluated the diagnostic value of CSF growth differentiation factor 15 (GDF15) in LM from lung adenocarcinoma (LUAD) and breast cancer (BC).
Haoyu Ruan, Jie Li, Fuhai Wang, Lei Zhang, Jie Luo, Yuan Mu, Ting Wang, Yuqing Wu, Jingping Liu, Yunyun Ning, Xuan Deng, Ming Guan, Jian Xu   +12 more
wiley   +1 more source

Omega-3 supplementation and cardiometabolic risk factors in obese/overweight children and adolescents: a GRADE assessed systematic review and meta-analysis

Nutrition & Metabolism
Background Omega-3 polyunsaturated fatty acids (ɷ3 PUFA), have been proposed as a supplement to improve cardiometabolic risk factors in obese/overweight children and adolescents. However, findings evidence remains inconsistent.
Vali Musazadeh, Mahsa Mahmoudinezhad, Pedram Pam, Sanaz Brazandeh, Fatemeh Faramarzi, Yousef Mohammadpour, Amir Hossein Faghfouri, Shahsanam Gheibi   +7 more
doaj   +1 more source

Maternal body mass index, gestational weight gain, and the risk of overweight and obesity across childhood: An individual participant data meta-analysis

PLoS Medicine, 2019
Background Maternal obesity and excessive gestational weight gain may have persistent effects on offspring fat development. However, it remains unclear whether these effects differ by severity of obesity, and whether these effects are restricted to the ...
E. Voerman, S. Santos, Bernadeta Patro Golab, P. Amiano, F. Ballester, H. Barros, A. Bergström, M. Charles, L. Chatzi, C. Chevrier, G. Chrousos, E. Corpeleijn, N. Costet, S. Crozier, G. Devereux, M. Eggesbø, S. Ekström, M. Fantini, S. Farchi, F. Forastiere, Vagelis Georgiu, K. Godfrey, D. Gori, V. Grote, W. Hanke, I. Hertz-Picciotto, B. Heude, D. Hryhorczuk, Rae-Chi Huang, H. Inskip, N. Iszatt, A. Karvonen, L. Kenny, B. Koletzko, L. Küpers, H. Lagström, I. Lehmann, P. Magnus, R. Majewska, J. Mäkelä, Y. Manios, F. Mcauliffe, S. McDonald, J. Mehegan, M. Mommers, C. S. Morgen, T. Mori, G. Moschonis, D. Murray, C. N. Chaoimh, E. Nøhr, A. Nybo Andersen, E. Oken, A. Oostvogels, A. Pac, E. Papadopoulou, J. Pekkanen, C. Pizzi, K. Polańska, D. Porta, L. Richiardi, S. Rifas-Shiman, L. Ronfani, A. Santos, M. Standl, C. Stoltenberg, E. Thiering, C. Thijs, M. Torrent, S. Tough, T. Trnovec, S. Turner, L. van Rossem, A. von Berg, M. Vrijheid, T. Vrijkotte, J. West, A. Wijga, J. Wright, O. Zvinchuk, T. Sørensen, D. Lawlor, R. Gaillard, V. Jaddoe   +83 more
semanticscholar   +1 more source

Historical birth records from 1896 to 1944 from the Basel maternity hospital, Switzerland, reveal significant obstetric selection pressures

The Anatomical Record, EarlyView.
Abstract Maternal and neonatal morbidity and mortality have declined dramatically during the last century. Historical data are therefore important sources to study the evolutionary selection pressures related to childbirth and how they have fluctuated over time.
Mirella Woodert, Guillermo Bravo Morante, Viktoria A. Krenn, Cédric Cordey, Nicole Torres‐Tamayo, Kaspar Staub, Nicole M. Webb, Martin Haeusler   +7 more
wiley   +1 more source

Can vitamin D supplementation affect cardiometabolic factors in children and adolescence with overweight and obesity? A grade-assessed systematic review and meta-analysis of randomized controlled trials

BMC Pediatrics
Background Vitamin D have been proposed as a supplement to improve cardiometabolic risk factors in obese/overweight children and adolescents. However, findings evidence remains inconsistent.
Amir Hossein Faghfouri, Mahsa Mahmoudinezhad, Pedram Pam, Sanaz Barazandeh, Fatemeh Faramarzi, Yousef Mohammadpour, Vali Musazadeh, Shahsanam Gheibi   +7 more
doaj   +1 more source

Human evolution and the obstetrical dilemma: The pelvic floor hypothesis

The Anatomical Record, EarlyView.
Abstract Human childbirth is mechanically difficult because a large‐headed, broad‐shouldered fetus must pass through a comparatively narrow, twisted bony birth canal. Traditional explanations of this “obstetrical dilemma” emphasize the role of bipedal locomotion in inhibiting the evolution of a wider, more spacious pelvis.
Barbara Fischer, Ekaterina Stansfield
wiley   +1 more source