Results 81 to 90 of about 1,752,397 (306)

Childhood Obesity [PDF]

BMJ, 1961
J. K. Lloyd, O. H. Wolff, W. S. Whelen
openaire   +7 more sources

Genetic Determinants of Childhood Obesity

Molecular Diagnosis & Therapy, 2020
Obesity represents a major health burden to both developed and developing countries. Furthermore, the incidence of obesity is increasing in children. Obesity contributes substantially to mortality in the United States by increasing the risk for type 2 ...
Sheridan H. Littleton, R. Berkowitz, S. Grant   +2 more
semanticscholar   +1 more source

Hierarchical Nanoplatform Integrating Oxidative–Acidic Microenvironment Remodeling and Bone Homeostasis Modulation for Diabetic Bone Defect Therapy

Advanced Science, EarlyView.
A hierarchical CM/LDH nanoplatform integrates ROS‐scavenging Ce‐MOF nanozymes with acid‐neutralizing CaAl‐LDH and is delivered within GelMA hydrogel to diabetic bone defects. By remodeling the oxidative‐acidic microenvironment, preserving mitochondrial homeostasis, and suppressing mtDNA–cGAS–STING inflammatory signaling, CM/LDH reduces proinflammatory ...
Xu Chen, Xingyu Zhu, Zhixin Qiu, Yijia Zhu, Xinhui Zheng, Dongqi Fan, Jinglei Zhan, Congxiu Mao, Ping Ji, Tao Chen, Qingqing He   +10 more
wiley   +1 more source

Transformer‐Based Multitask Framework Integrating Habitat and Deep Learning for Predicting Early Disease Control and Survival in Immunotherapy‐Treated Hepatocellular Carcinoma

Advanced Science, EarlyView.
This study developed ECOS‐Net, a transformer‐based multitask framework integrating CT‐derived habitat and 2.5D deep learning features to simultaneously predict early disease control and overall survival in hepatocellular carcinoma patients treated with immune checkpoint inhibitors.
Xiaona Fu, Yusheng Guo, Bingxin Gong, Jie Lou, Ning Wang, Xuejun Chen, Hongtao Hu, Rundong Wang, Xiaofang Guo, Shanmei Li, Yangyang Xie, Shichao Long, Mengsi Li, Shubo Pan, Wen Shen, Zhaogang Zhang, Zifang Song, Pengchen Liang, Xiaoyun Liang, Peng Sun, Guilin Zhang, Shanshan Jiang, Jinxiang Zhang, Lian Yang   +23 more
wiley   +1 more source

Childhood obesity, cardiovascular and liver health: a growing epidemic with age

World Journal of Pediatrics, 2020
Background The frequency of childhood obesity has increased over the last 3 decades, and the trend constitutes a worrisome epidemic worldwide. With the raising obesity risk, key aspects to consider are accurate body mass index classification, as well as ...
M. Faienza, M. Chiarito, Emilio Molina-Molina, Harshitha Shanmugam, F. Lammert, M. Krawczyk, G. D'Amato, P. Portincasa   +7 more
semanticscholar   +1 more source

Context‐Dependent Inverse Association of Glucose–Lipid Metabolic Status With Anemia: Evidence From Multinational Multicohort Analyses

Advanced Science, EarlyView.
Across six multinational cohorts, higher triglyceride–glucose index values are consistently associated with lower prevalent and incident anemia, despite their established adverse cardiometabolic significance. This inverse relationship varies across inflammatory, cardiovascular, and renal contexts, suggesting that glucose–lipid metabolic status carries ...
Guosong Jiang, Xinxing Wang, Lianfeng Xie, Wenna Ding, Yingyong Yin, Mei Yao, Zhibo Cui, Kaiqiang Tang, Lijie Zhong, Zhi Wang, Jia Wang, Lei Lei, Xiaoxiao Qu, Chi‐E. Qiu   +13 more
wiley   +1 more source

Adherence to physical activity and screen time recommendations of youth: Demographic differences from National Health and Nutrition Examination Survey 2017–2018

Obesity Science & Practice
Background Engaging in physical activity (PA) and reducing sedentary behaviors among youth are linked to improved mental and physical health.
Amin Mokari‐Yamchi, Keith Brazendale, Amir Hossein Faghfouri, Yousef Mohammadpour, Shahsanam Gheibi   +4 more
doaj   +1 more source

Association between Characteristics at Birth, Breastfeeding and Obesity in 22 Countries: The WHO European Childhood Obesity Surveillance Initiative – COSI 2015/2017

Obesity Facts, 2019
Background: In Europe, although the prevalence of childhood obesity seems to be plateauing in some countries, progress on tackling this important public health issue remains slow and inconsistent.
A. Rito, M. Buoncristiano, A. Spinelli, B. Salanave, M. Kunešová, Tatjana Hejgaard, Marta García Solano, A. Fijałkowska, L. Sturua, J. Hyska, C. Kelleher, V. Duleva, S. Musić Milanović, Victoria Farrugia Sant'Angelo, Shynar Abdrakhmanova, Enisa Kujundzic, V. Peterkova, A. Gualtieri, I. Pudule, A. Petrauskienė, Maya Tanrygulyyeva, Rakhmatulloev Sherali, Constanta Huidumac-Petrescu, Julianne Williams, W. Ahrens, J. Breda   +25 more
semanticscholar   +1 more source

LncRNA FLJ20021 Restrains Fibroblast Senescence and Matrix Remodeling in Pelvic Organ Prolapse by Promoting XRCC6‐Dependent ADI1 Transcription

Advanced Science, EarlyView.
FLJ20021 interacts with XRCC6 to regulate ADI1 transcription and downstream cellular phenotypes in hUSLFs. Reduced FLJ20021 in POP is associated with lower ADI1, increased apoptosis, senescence, and an ECM‐degrading marker profile. Conversely, FLJ20021 overexpression enhances XRCC6‐dependent ADI1 expression, reduces apoptosis and senescence, and shifts
YanFeng Yang, BingJie Rui, GuangHai Rui, YiNan Duan, Ji Hyang Kim   +4 more
wiley   +1 more source

The epidemiological burden of obesity in childhood: a worldwide epidemic requiring urgent action

BMC Medicine, 2019
BackgroundIn recent decades, the prevalence of obesity in children has increased dramatically. This worldwide epidemic has important consequences, including psychiatric, psychological and psychosocial disorders in childhood and increased risk of ...
M. di Cesare, M. Sorić, P. Bovet, J. Miranda, Z. Bhutta, G. Stevens, A. Laxmaiah, A. Kengne, J. Bentham   +8 more
semanticscholar   +1 more source