Results 51 to 60 of about 57,967 (247)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Child Support Right In The Human Rights Perspective

SASI
Introduction: The provision of Article 28 B paragraph (2) and Article 28 D paragraph (1) of the 1945 Constitution of the Republic of Indonesia can be stated as the philosophical basis for children's rights on viability, growth, and development; and the ...
Arief Syahrul Alam, Muhamad Chaidar, Anisah Che Ngah   +2 more
doaj   +1 more source

Theorising children’s participation: Trans-disciplinary perspectives from South Africa

Perspectives in Education, 2011
From text: Children’s participation is a popular rallying cry among child rights activists and community development groups, backed by the recognition of children’s participatory rights in the United Nations Convention on the Rights of the Child (UNCRC).
Patricia Henderson, Shirley Pendlebury, E. Kay M. Tisdall   +2 more
doaj   +3 more sources

Allt eller inget? Barns rättigheter i lärarutbildning

Utbildning & Demokrati, 2020
In 2020, the United Nations Convention on the Rights of the Child (UNCRC) is incorporated into Swedish law. In the proposals for new legislation, capacity building was emphasized to generally develop knowledge about children’s rights among professionals ...
Åsa Olsson, Helene Elvstrand, Nina Thelander   +1 more
doaj   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Caregivers' views on the risk factors impeding implementation of provision rights in children's homes in Harare, Zimbabwe

Social Sciences and Humanities Open
This article focuses on caregivers' views on the risk factors impeding the implementation of children's provision rights in the early childhood development phase in seven children's homes in Harare, Zimbabwe.
Blessing Tendai Baloyi, Jace Pillay, Lucia Munongi   +2 more
doaj   +1 more source

MODERASI DALAM MEMAKNAI HAK-HAK ANAK

Moderatio, 2022
This paper discusses the concept of moderation in addressing children's rights in terms of family, environment and society. This paper uses a descriptive qualitative research method that is literary in nature.
Siti Nurjanah
doaj  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

The Children Right Violation in the Conflict of Sudan: Government Negligence

Sociological Jurisprudence Journal
The conflict caused by the government's negligence in handling political issues that have an impact on the welfare of children's rights that should be obtained, research uses a normative approach method.
Yordan Gunawan, Danu Fernando, Rahmawati Mayta Wardani, Mohammad Hazyar Arumbinang   +3 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source