Results 21 to 30 of about 4,290,922 (246)
Children’s play and democratic culture
, 2018 Children’s play has figured on innumerable occasions as one of the principal focal points for research on different approaches to human development.
Camas Garrido, Laura
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FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Консультативная психология и психотерапия, 2015 The article presents an attempt to identify the main characteristics of children’s information environment and show their influence on the psychology of modern children.
Smirnova E.O.
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Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Children’s participation in the design of physical activities conducted in the outdoors. [PDF]
, 2012 Background: Despite recent UK Governmental policy changes concerning the amount of outdoor, physical activity children are currently engaged in (LTS, 2010), there is a gap in the academic literature concerning children’s personal preferences for ...
Bruce, Fraser +2 more
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Zostań MovieStarPlanet! – czyli o partycypacji kultury dziecięcej w kulturze cyfrowej
Problemy Wczesnej Edukacji, 2018 This article reflects on the specificity of contemporary children’s participation in digital culture. It comprises study results, whose aim was the reconstruction of children’s culture created by children during internet communication in the ...
Joanna Dziekońska
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
IMAGINAÇÃO E PROTAGONISMO NA EDUCAÇÃO INFANTIL: CONSTRUÇÃO DE VÍNCULOS ENTRE ADULTOS E CRIANÇAS
Colloquium Humanarum, 2014 This research was carried out at the Graduate Program in Education of FCT / UNESP. The study was conducted at two institutions Childhood Education from two cities of São Paulo and arose from an action research that proved the lack of appreciation and ...
Tony Aparecido Moreira +3 more
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Leksikon Klasik pada Permainan Anak di Masyarakat Budaya Minangkabau
Jurnal Antropologi: Isu-Isu Sosial Budaya, 2021 The lexicon is an important part of the heritage of local wisdom which is also important in culture-based children's education. This article, it is explained the classic lexicon of children's games in Minangkabau culture and the cultural significance of ...
Rona Almos, Sonezza Ladyanna
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