Results 61 to 70 of about 5,675,213 (309)
Arthritis Research & TherapyBackground Facet joint osteoarthritis (OA) is prevalent in patients with adolescent idiopathic scoliosis (AIS). The most pronounced OA presents above and below the curve's apex where the intervertebral rotation is the greatest.
Kai Sheng +9 more
doaj +1 more source
Frontiers in Oncology, 2013 Epigenetic drugs like histone deacetylase inhibitors and DNA methyltransferase inhibitors have been shown to be effective against a variety of tumor entities.
Matthias Manuel Pfeiffer +4 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Children\u27s Mercy Hospital Annual Report 2006
, 2007 oai:scholarlyexchange.childrensmercy.org:cmh-annual-reports-1000Annual report for The Children\u27s Mercy Hospital in Kansas City MO, a pediatric medical center.https://scholarlyexchange.childrensmercy.org/cmh-annual-reports/1000/thumbnail ...
Children\u27s Mercy Hospital
core +1 more source
Guidelines for library service for young adults
BiD: Textos Universitaris de Biblioteconomia i Documentació, 2001 Directrius per a la planificació i avaluació de serveis adreçats a adolescents en biblioteques ...
IFLA. Section of Library for Children and Young Adults
doaj
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Food Allergy as a Preformation Factor For Bronchial Asthma Diagnosis in Children
Zdorovʹe Rebenka, 2015 There was reviewed literature data on development and diagnosis of food allergy in children with bronchial asthma to optimization remedial rehabilitation measures.
V.M. Levitsky +4 more
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Characterization of Key Sexually Dimorphic Regulators in Pain Processing
Canadian Journal of Pain, 2019 Introduction/Aim: Chronic pain affects 1 in 5 Canadians and costs over $43B annually, yet effective and safe treatment options remain elusive. Recent discoveries have brought to the forefront sex differences in mechanisms of pain as a potential ...
Shahrzad Ghazisaeidi +12 more
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source