Results 71 to 80 of about 5,675,213 (309)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Sexual and Reproductive Health Matters, 2019 The political situation in Yemen has been precarious since 2011 when popular protest broke out amid the Arab Spring, calling for President Saleh to step down.
Catherine N Morris +4 more
doaj +1 more source
Clinical Orthopaedics and Related Research, 1995 Advances in microsurgical techniques have permitted replantation and reconstructive procedures to restore amputated or injured parts with a high degree of success in children. Despite this progress, some technical concerns remain. During a 15-year period, replantations were done in 53 children with major limb (18), hand (10), or digit (25) amputations.
Beris, A. E. +2 more
openaire +3 more sources
FEBS Open Bio, EarlyView.Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar +4 more
wiley +1 more source
Handbook of best practice in Children Act cases.
, 1997 Implementation of the Children Act 1989, which came into force on 1 October 1991, required a fundamental change of approach by the courts, and by everyone working on cases in which children were involved. The Children Act Advisory Committee was set up
Children Act Advisory Committee
core
“...as a good parent would...” [PDF]
, 2015 This inquiry headed by Principal Commissioner, Bernie Geary OAM, addresses the issue of sexual abuse, exploitation and the adequacy of the provision of residential care services to Victorian children and young people in care.
Commission for Children and Young People (Vic)
core
Children\u27s Mercy Annual Report 1999
, 2000 Annual report for The Children\u27s Mercy Hospital in Kansas City MO, a pediatric medical center.https://scholarlyexchange.childrensmercy.org/cmh-annual-reports/1016/thumbnail ...
Children\u27s Mercy Hospital
core +1 more source
International Journal of Population Data Science, 2018 Introduction Increasingly, communities are designing and implementing contextualized approaches to integrated service delivery. Having communities in the lead is critical to successful design and implementation.
Naomi Parker +4 more
doaj +1 more source