Results 81 to 90 of about 4,545,027 (267)
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Wilderness School annual report. 2010.
, 2010 Annual; Began with Feb. 2010.; "Submitted to the State Advisory Council on Children and Families pursuant to Section 17a-32a of the Connecticut General Statutes."; Harvested from the web on 11/19 ...
Wilderness School (Connecticut Dept. of Children and Families)
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Always was, always will be Koori Children [PDF]
, 2016 This report has been published by the Commission for Children and Young People (CCYP) Victoria. It documents the findings of Taskforce 1000, which was an eighteen month project that critically reviewed the case plans and circumstances of 980 ...
Commission for Children and Young People (Vic)
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Вопросы современной педиатрии, 2014 The article describes the monitoring of severe cryopyrin-associated syndrome (syndrome CINCA/NOMID). The following clinical case indicates successful application of homogeneous antibodies to interleukin 1 — canakinumab — in patient with chronic ...
T. V. Sleptsova +12 more
doaj +1 more source
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Features of children perinatally infected with HIV-1 surviving longer than 5 years
, 1994 Children infected with HIV do not necessarily develop AIDS to a set pattern but can be divided into long-term and short-term survivors. We examined long-term survival in children perinatally infected with HIV-1.
DUSE, MARZIA +1 more
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FEBS Open Bio, EarlyView.Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar +4 more
wiley +1 more source
, 2015 application/pdf; "March 12, 2015."; Testimony before the Kansas Legislature, House Committee on Children and Seniors, presented by Phyllis Gilmore, Secretary, Kansas Department for Children and Families."The Kansas Department for Children and Families ...
Gilmore, Phyllis.
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