Results 71 to 80 of about 9,035,003 (377)
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam+9 more
wiley +1 more source
Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson+11 more
wiley +1 more source
The Children’s Perspectives Protocol: A participatory approach to studying child work issues [PDF]
This is the summary of a research protocol constructed as part of the Radda Barnen project "Children’s perspectives on their working lives", originally published in 1998.
Woodhead, Martin
core
Pursuing the adoption pathway: the lived experiences of people living with HIV [PDF]
No description ...
Children Act+4 more
core +1 more source
TangToys: Smart Toys that can Communicate and Improve Children's Wellbeing [PDF]
Children can find it challenging to communicate their emotions especially when experiencing mental health challenges. Technological solutions may help children communicate digitally and receive support from one another as advances in networking and sensors enable the real-time transmission of physical interactions. In this work, we pursue the design of
arxiv
Mobile Apps for Children's Health and Wellbeing: Design Features and Future Opportunities [PDF]
Mobile health apps hold great potential for promoting children's health and wellbeing. However, there is limited understanding of how these technologies are currently designed to support children with their health concerns or wellness goals. To gain insight into the current landscape of mobile apps designed for children's health, we retrieved and ...
arxiv
We introduce an immunohistochemistry method to measure autophagy flux, highlighting the active degradation and recycling of cellular waste. This cost‐effective approach uses tissue samples to track key markers like LC3 and SQSTM1, revealing how cells maintain health or respond to diseases such as cancer. It bridges the gap between research and clinical
Shahla Shojaei+6 more
wiley +1 more source
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang+9 more
wiley +1 more source
Background Mid-Upper Arm Circumference (MUAC) is an independent anthropometric measurement used to identify malnutrition in children. While much research has been dedicated to applying fixed estimates of MUAC to identify cases of malnutrition in children
Mikaela A. Miller+4 more
doaj +1 more source
Neurological Involvement Complicating Invasive Pulmonary Aspergillosis
Cerebral aspergillosis is a fungal infection with a bad prognosis. It usually occurs in immunocompromised patients and manifests itself .Cross-sectional imaging reveals suggestive lesions.
Ibrahima Dokal Diallo+5 more
doaj +1 more source