Results 61 to 70 of about 2,009,269 (311)

Academic attainment and special educational needs in extremely preterm children at 11 years of age : the EPICure Study [PDF]

open access: yes, 2009
Aim: To assess academic attainment and special educational needs (SEN) in extremely preterm (EP) children in middle childhood. Methods: Of 307 EP (=25 weeks) survivors born in the UK and Ireland in 1995, 219 (71%) were re-assessed at 11 years, with a
Hennessy, Enid M.   +5 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Effectiveness of MURDER Method on the Improvement of Academic Performance of Children with Spelling Learning Disorder [PDF]

open access: yesInterdisciplinary Journal of Virtual Learning in Medical Sciences, 2015
Introduction: One of the most important strategic goals for actualizing learners' potential abilities is using meta cognitive skills. The purpose of the present study is to examine the effect of education of Murder on the improvement of academic ...
Leila Karimi Jozestani   +2 more
doaj  

Effect of frankincense oil on the neurochemical changes induced in rat model of status epilepticus

open access: yesClinical Phytoscience, 2020
Background The current objective is to evaluate the effect of frankincense oil on the convulsions and the associated neurochemical alterations produced in pilocarpine-induced status epilepticus rat model. Methods Rats were divided randomly into: control,
Eman N. Hosny   +4 more
doaj   +1 more source

Virtual Reality for Children with Special Needs

open access: yes, 2022
ICCHP-AAATE 2022 Open Access Compendium "Assistive Technology, Accessibility and (e)Inclusion" Part I / Petz, Andrea ; Hoogerwerf, Evert-Jan ; Mavrou, Katerina, Seite 64 ...
Bosse, Ingo K.   +2 more
openaire   +2 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

The Effectiveness of Reading Improvement Comprehensive Program on the Success and Academic Resilience of Students with Dyslexia

open access: yesTaḥqīqāt-i ̒Ulūm-i Raftārī, 2018
Aim and Background: Dyslexia has many effects on students' psychological status in addition to academic problems. Regarding this issue, the present study aimed to develop a Reading Improvement Comprehensive Program (RICP) and its effectiveness on the ...
Khodabakhsh Heidari   +4 more
doaj  

The Effectiveness of Dweck’s Mind Set Intervention on Students’ Negative Orientation Towards Problem and Hopelessness during the COVID-19 [PDF]

open access: yesپژوهش‌های کاربردی روانشناختی
Aim: The aim of the present study was to investigate the Effectiveness of Dweck’s Mindset intervention on negative orientation towards problem and hopelessness in high school students.
Bahar Rashidi   +2 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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