Results 51 to 60 of about 43,846 (311)

Survival mechanisms to selective pressures and implications

open access: yesOpen Life Sciences, 2018
Organisms have evolved a spectrum of strategies that facilitate survival in the face of adverse environmental conditions. In order to make full use of the unfavorable resources of nature, human beings usually impose selective pressures to breed ...
Xie Songbo, Liu Min
doaj   +1 more source

DNA Damage Inducible Protein 1 is Involved in Cold Adaption of Harvested Cucumber Fruit

open access: yesFrontiers in Plant Science, 2020
Chilling stress can cause cellular DNA damage, affecting the faithful transmission of genetic information. Cold acclimation enhances chilling tolerance, but it is not clear that the process of cold adaption involves DNA damage responses, as cold ...
Bin Wang   +3 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Research Progress on the Regulatory Mechanism of Very Fast Chilling on the Tenderness of Postmortem Muscle [PDF]

open access: yesShipin Kexue
Chilling is an essential process in chilled meat production, and various chilling methods are available for actual production. Different chilling methods have different effects on meat quality.
XIAO Zhiyuan, ZHANG Dequan, YAN Tongjing, XU Yuqian, LI Xin, LIU Shanshan, YANG Qingfeng, HOU Chengli
doaj   +1 more source

Sorghum (Sorghum bicolour L.) Germination Dynamics at Extreme Temperatures

open access: yesProceedings, 2020
Water and heat stressors during flowering are predominant limitations of dryland sorghum yields across Australia’s north-eastern cropping zone. Crops sown early could flower before seasonal heatwaves, but the seed must uniformly germination and ...
Mengwei Li   +3 more
doaj   +1 more source

BUMPY STEM Is an Arabidopsis Choline/Ethanolamine Kinase Required for Normal Development and Chilling Responses

open access: yesFrontiers in Plant Science, 2022
Phospholipid biosynthesis is a core metabolic pathway that affects all aspects of plant growth and development. One of the earliest step in this pathway is mediated by choline/ethanolamine kinases (CEKs), enzymes in the Kennedy pathway that catalyze the ...
Christina Rabeler   +2 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Regulation of photosynthesis and antioxidant metabolism in maize leaves at optimal and chilling temperatures : review

open access: yes, 2002
Maize (Zea mays L.) is a chilling (below 15 °C) sensitive plant that shows little capacity to acclimate to low growth temperatures. Maize leaves are extremely sensitive to chilling injury, which usually results in premature leaf senescence.
Foyer, C. H.   +5 more
core   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

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