Results 181 to 190 of about 9,673 (285)

Physiological and Transcriptome Analyses of CaCl₂ Treatment to Alleviate Chilling Injury in Pineapple. [PDF]

Plants (Basel), 2022
Zhang M, Zhang Q, Tian C, Liu G, Pan Y, Xu X, Shi X, Zhang Z, Meng L.   +8 more
europepmc   +1 more source

Hyperlipidemia Aggravates Alveolar Bone Loss via Periodontal Ligament Stem Cell Ferroptosis Through GSK3β Dependent Ubiquitin‐Mediated NRF2 Degradation

Advanced Science, EarlyView.
Lipid metabolic stress triggers ferroptosis in PDLSCs through the GSK3β/NRF2 pathway, thereby aggravating periodontal bone loss. Upregulated GSK3β promotes NRF2 ubiquitination and proteasomal degradation via β‐TrCP, suppressing NRF2 nuclear translocation and antioxidant target expression.
Yuxiao Zhang, Xiangyao Wang, Yaxin Wu, Liping Liu, Gaoshaer Nuerlan, Ahsawle Ozathaley, Xiaorui Zhang, Jinping Wang, Bowen Yang, Jing Mao, Yan Liu, Shiqiang Gong   +11 more
wiley   +1 more source

JAZ2/JAZ4-MYC2.1 module mediates MeJA-induced alleviation of chilling injury in peach fruit (<i>Prunus persica</i>). [PDF]

Hortic Res
Li A, Wang H, Badrunnesa A, Meng J, Gao Y, Sun S, Niu L, Pan L, Duan W, Cui G, Wang Z, Zeng W.   +11 more
europepmc   +1 more source

Fucoidan treatment alleviates chilling injury in cucumber by regulating ROS homeostasis and energy metabolism. [PDF]

Front Plant Sci, 2022
Lin D, Yan R, Xing M, Liao S, Chen J, Gan Z.   +5 more
europepmc   +1 more source

ACLY‐Driven Metabolic Reprogramming Promotes Histone Acetylation and Inflammation‐Associated Fibrosis in Chronic Kidney Disease

Advanced Science, EarlyView.
This study reveals a citrate–ACLY–H3K27ac metabolic–epigenetic axis driving inflammatory gene activation and kidney fibrosis, highlighting ACLY inhibition as a potential therapeutic strategy for chronic kidney disease (CKD). ABSTRACT The mechanisms by which metabolic stress drives epigenetic dysregulation and fibrosis in chronic kidney disease (CKD ...
Chunxiu Du, Dhanunjay Mukhi, Lingzhi Li, Chenyu Li, Siyu Pan, Bernhard Dumoulin, Eunji Ha, Lakshmi P Kolligundla, Yanjuan Hou, Jonathan Levinsohn, Chaelin Kang, Konstantin Adrian Klötzer, Junnan Wu, Samer Mohandes, Kathryn E Wellen, Katalin Susztak   +15 more
wiley   +1 more source

A New Regulatory Network Controls Chilling Injury in Peach Fruit by γ-Aminobutyric Acid. [PDF]

Foods, 2023
Song C, Zhou C, Pan Y, Yang Z.
europepmc   +1 more source

Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus

Advanced Science, EarlyView.
This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan, Dong Zhou, Ran Shao, Xing Liu, Jin Peng, Yingran Huang, Shuhui Qi, Cankun Xi, Menghang Wang, Bin Sun, Yinglin Qi, Xin Yin   +11 more
wiley   +1 more source

Combined treatment of heat shock and glycine betaine recovered chilling injury in banana fruit by reducing membrane damage. [PDF]

Food Chem X
Niaz N, Hu W, Pan S, Ali K, Walayat N, Mohamed Ahmed IA, Niaz S, Zhang J, Cao Y.   +8 more
europepmc   +1 more source

Melatonin Treatments Reduce Chilling Injury and Delay Ripening, Leading to Maintenance of Quality in Cherimoya Fruit. [PDF]

Int J Mol Sci, 2023
Medina-Santamarina J, Guillén F, Ilea MIM, Ruiz-Aracil MC, Valero D, Castillo S, Serrano M.   +6 more
europepmc   +1 more source

Mechanically Triggered DNA Nanovehicles for Targeted Dual‐Drug Cancer Therapy

Advanced Science, EarlyView.
A mechanically triggered DNA nanovehicle is introduced that co‐releases two anticancer drugs in response to integrin‐mediated cellular forces. Cholesterol‐anchored DNA assemblies undergo force‐induced unfolding at cell–cell junctions, enabling selective, localized dual‐drug activation in cancer cells while minimizing off‐target toxicity in low‐tension ...
Murali Mohana Rao Singuru, Priyanka Bhattacharyya, Mingxu You   +2 more
wiley   +1 more source