Results 41 to 50 of about 61,204 (282)

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

The effect of traditional handling, processing and storage methods on the quality of dried fish in small scale fisheries in Nigeria [PDF]

open access: yes, 1999
Most of the fish marketed throughout Nigeria are in either smoked or dried form. The technological requirement for other forms of preservation like chilling and freezing cannot be afforded by the small scale fisher folk.
Eyo, A.A.
core  

Seleção de genótipos de pessegueiro F1 com baixa necessidade de frio hibernal Selection of F1 peach genotypes with low chilling requirements

open access: yesRevista Brasileira de Fruticultura, 2009
A baixa necessidade de frio é característica fundamental para que se possa cultivar economicamente o pessegueiro em condições de clima subtropical, devendo ser este, portanto, o principal objetivo dos programas de melhoramento nestas regiões.
Américo Wagner Júnior   +5 more
doaj   +1 more source

Genetic Dissection of Bloom Time in Low Chilling Sweet Cherry (Prunus avium L.) Using a Multi-Family QTL Approach

open access: yesFrontiers in Plant Science, 2020
Bloom time in sweet cherry (Prunus avium L.) is a highly heritable trait that varies between genotypes and depends on the environmental conditions.
Alejandro Calle   +5 more
doaj   +1 more source

Chilling Requirements to Relieve Bud Dormancy in Black-fruited Aronia Taxonomic Groups Is Related to Ploidy and Geographic Origin

open access: yesHortScience, 2023
The genus Aronia Medik., also known as chokeberry, is a group of deciduous shrubs in the Rosaceae family, subtribe Malinae. The two commonly accepted black-fruited Aronia species are black chokeberry [Aronia melanocarpa (Michx.) Elliott] and aroniaberry [
Jonathan D. Mahoney   +2 more
doaj   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Apple Cultivation in Nontraditional Areas: Novel Perspectives and Advances A review

open access: yesJournal of Horticultural Research
Low-chilling apple genotypes have become a viable alternative for cultivation in regions with moderate to mild winters due to concerns about the impact of global climate change.
Thakur Praveen   +3 more
doaj   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

Influence of climate change on the flowering of temperate fruit trees [PDF]

open access: yes, 2012
It is well known that winter chilling is necessary for the flowering of temperate trees. The chilling requirement is a criterion for choosing a species or variety at a given location.
Centeno Muñoz, Ana   +5 more
core  

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

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