Results 41 to 50 of about 6,441 (267)

Modeling and validation of an active chilled beam terminal unit

Journal of Building Engineering, 2019
Abstract In this paper, a simplified hybrid model is proposed for an active chilled beam (ACB) terminal unit. Based on the conservation equations of mass and energy, the model demonstrates the air entrainment characteristics in the air chamber and the heat transfer process in cooling coil.
Ji, Ke, Cai, Wenjian, Zhang, Xin, Wu, Bingjie, Ou, Xianhua   +4 more
openaire   +3 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Energy Conservation Using Variable-speed Chilled Water Pumps for Single-loop Chilled Water Systems with Fan-coil Units

Energy Engineering, 2003
ABSTRACT This article addresses the need to reduce energy consumption by chilled water pumps in air conditioning systems. In particular, this article considers the use of variable-speed pumping systems. Many office buildings in China utilize air conditioning systems with fan-coil units (FCUs) and a primary/secondary chilled water system without ...
Weifeng Zhu, Yi Jiang
openaire   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Avaliação da necessidade de frio de pessegueiro por meio de ramos enxertados Evaluation of chilling requirement in peach through grafted twigs

Revista Brasileira de Fruticultura, 2009
As metodologias utilizadas para a avaliação da necessidade de frio hibernal apresentam algumas limitações quanto à sua aplicabilidade. Este trabalho teve como objetivo avaliar a necessidade de frio em seis cultivares de pessegueiro ('Rei da Conserva ...
Américo Wagner Júnior, Claudio Horst Bruckner, Luiz Carlos Chamhum Salomão, Leonardo Duarte Pimentel, José Osmar da Costa Silva, Carlos Eduardo Magalhães dos Santos   +5 more
doaj   +1 more source

Estimation of Blooming Start with the Adaptation of the Unified Model for Three Apricot Cultivars (Prunus armeniaca L.) Based on Long-Term Observations in Hungary (1994–2020)

Diversity, 2022
The aim of our research was to adapt Chuine’s unified model to estimate the beginning of blooming of three apricot cultivars (‘Ceglédi bíborkajszi’, ‘Gönci magyar kajszi’, and ‘Rózsakajszi C.1406’) in Hungary in the time period 1994–2020.
Ildikó Mesterházy, Péter Raffai, László Szalay, László Bozó, Márta Ladányi   +4 more
doaj   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

An optimal plate fin heat exchanger for adsorption chilling: Theoretical consideration

International Journal of Thermofluids, 2022
Adsorption heat transformation (AHT) makes it possible to accumulate and use renewable energy and waste heat. This emerging technology is based on the reversible adsorption-desorption of vapour by an adsorbent.
A. Grekova, M. Tokarev
doaj   +1 more source