Results 121 to 130 of about 121,509 (248)

Flow cytometry‐based monitoring of chimeric antigen receptor (CAR) T cells: Reagent selection, assay design, and clinical utility

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Accurate quantification of chimeric antigen receptor (CAR) T cells is essential for monitoring post‐infusion CART expansion and persistence and for real‐time clinical decision‐making. Multiparameter flow cytometry (MFC) enables rapid, live‐cell detection with absolute quantification and concurrent immunophenotypic characterization. This review
Jianhua Ling, Wei Wang, Sa A. Wang
wiley   +1 more source

Chimeric Antigen Receptor T Cells as Living Therapeutics Targeting Senescence and Age-Related Diseases. [PDF]

Research (Wash D C)
Shao Q, Chen D, Shao W, Ye Q.
europepmc   +1 more source

Goofy/123Cre lineage tracing differentiates olfactory and vomeronasal neurons from GnRH‐1 and terminal nerve neurons during neuronal migration and reveals additional olfactory placode‐derived cells in the brain

Developmental Dynamics, EarlyView.
Abstract The olfactory placode (OP) generates a broad array of chemosensory neurons in the nasal region, including olfactory sensory neurons, vomeronasal sensory neurons, neurons of the septal organ, and Grueneberg ganglion. During invagination, the OP also generates migratory neuronal populations, including gonadotropin‐releasing hormone‐1 (GnRH‐1 ...
Enrico Amato Jr., Mia V. Call, Noah M. LeFever, Mya Aviles‐Carlos, Nikki M. Dolphin, Paolo E. Forni   +5 more
wiley   +1 more source

Chimeric Antigen Receptor T-Cells in Myasthenia Gravis: Advances, Safety Challenges, and Future Directions. [PDF]

Muscle Nerve
Hegelmaier T, Duscha A, Desel C, Stassen S, Krzemien T, Hennemann AK, Pappa V, Haghikia A.   +7 more
europepmc   +1 more source

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler, Friederike Zimmermann, Bettina Heidecker, Ulf Landmesser, Arash Haghikia   +4 more
wiley   +1 more source

The Pleiotropic Roles of Cytokines in Chimeric Antigen Receptor T-cell Therapy. [PDF]

Cancer Immunol Res
Stewart CM, Siegler EL, Kenderian SS.
europepmc   +1 more source

Enhancing Optogenetics‐Based Cancer Therapy Via Nanotechnology

Exploration, EarlyView.
Nanotechnology enhances optogenetics‐based cancer therapy through improved delivery systems and non‐invasive optical regulation. It further enables precise and programmable control of optogenetic living therapeutics for localized antitumor responses.
Honggang Shen, Wenzhe Yi, Rongzhang Li, Shuangshuang Hu, Xindi Qian, Dan Yan, Qian Zou, Guanru Wang, Yaping Li   +8 more
wiley   +1 more source

Editorial: Novel chimeric antigen receptor (CAR) designs in engineering NK cells for cancer. [PDF]

Front Immunol
Chan WK.
europepmc   +1 more source

Immune Markers and Risk of Pancreatic Cancer in the European EPIC Cohort

International Journal of Cancer, EarlyView.
The immune system has been implicated as a major driver in pancreatic cancer etiology. Previous cohort studies have found associations between pancreatic cancer and single immune system‐derived markers, but omics‐based evidence remains scarce. In this prospective case–control study, the authors investigated 92 proteins involved in immune reactions and ...
Verena A. Katzke, Yue Chen, Srimanti Dutta, Federico Canzian, Julie Louise Munk Andersen, Agnetha Linn Rostgaard‐Hansen, Léa Bouteille, Vinciane Rebours, Thérèse Truong, Matthias B. Schulze, Benedetta Bendinelli, Valeria Pala, Vittorio Simeon, Rosario Tumino, Carlotta Sacerdote, Roel Vermeulen, P. Martijn Kolijn, Sjoerd G. Elias, Marta Crous‐Bou, Maria‐José Sánchez, Ana Jimenez‐Zabala, José María Huerta, Marcela Guevara, Nick Wareham, Marie Breeur, Mattias Johansson, James Yarmolinsky, Daniele Campa, Rudolf Kaaks   +28 more
wiley   +1 more source

Targeting amyloid-β pathology by chimeric antigen receptor astrocyte (CAR-A) therapy. [PDF]

Science
Chen Y, Liu Y, Nguyen K, Wu J, Song S, Lin K, Rodrigues PF, Du S, Zhou C, Xiong K, Bosch M, Lin PB, Khantakova D, Wu S, Wu M, Yuede C, Holtzman DM, Colonna M.   +17 more
europepmc   +1 more source