Chimeric Antigen Receptor T-Cell Therapy: More Than an Anti-Cancer Drug. [PDF]
Schenk HCM +8 more
europepmc +1 more source
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu +5 more
wiley +1 more source
Involvement of the hospital pharmacist in securing the chimeric antigen receptor (CAR)-T cell circuit. [PDF]
Bryla A +4 more
europepmc +1 more source
Targeting the intratumoral microbiota to overcome cancer immunotherapy resistance
This review delineates the mechanisms of intratumoral microbiota in cancer immunotherapy resistance, and offers strategies for microbiota‐targeted precision immunotherapy. Abstract Cancer remains a significant global health threat. The tumor microenvironment (TME) is a sophisticated ecological niche that exerts a pivotal effect on treatment outcomes ...
Bufu Tang +14 more
wiley +1 more source
Facts and Hopes of Chimeric Antigen Receptor-Redirected NK T Cells. [PDF]
Courtney AN +5 more
europepmc +1 more source
This study developed and assessed a new multiplex assay for the simultaneous detection of antibodies against multiple Human Papillomavirus (HPV) types. Using recombinant L1 protein, the assay quantifies IgG and IgA responses in human plasma, enabling comprehensive immune profiling across multiple high‐risk cancer‐associated HPV genotypes. This approach
Arash Aslanabadi +11 more
wiley +1 more source
Myeloid-derived immunosuppression of chimeric antigen receptor T cells in the neuronal microenvironment of glioblastoma. [PDF]
Zhang J +8 more
europepmc +1 more source
The Regulatory Role and Mechanism of Myoferlin in Mitophagy During Papillary Thyroid Carcinogenesis
ABSTRACT Papillary thyroid carcinoma (PTC) is the most prevalent subtype of thyroid cancer; however, the regulatory mechanisms by which mitophagy influences its progression remain inadequately elucidated. This study sought to examine the role of myoferlin (MYOF) in mitophagy and its molecular basis during PTC development. Utilizing three paired PTC and
Wen‐Chao Lyu +6 more
wiley +1 more source
Advancements in delivery systems for in vivo chimeric antigen receptor T-cell therapy in urological diseases. [PDF]
Li Y, Zhang W, Tang D.
europepmc +1 more source
Advances and challenges of chimeric antigen receptor T cell therapy in digestive system malignancies. [PDF]
Wang C +4 more
europepmc +1 more source

