Results 131 to 140 of about 1,289,528 (197)
Abstract Sustainable aquafeed development requires alternative protein sources that reduce dependence on fishmeal without compromising shrimp performance. This study evaluated shrimp by‐product meal (SBM) as a fishmeal replacer in juvenile Pacific white shrimp (Penaeus vannamei) and assessed their responses to acute air exposure stress.
Deni Aulia +12 more
wiley +1 more source
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng +14 more
wiley +1 more source
Cholesterol‐enriched plasma membranes in hepatocellular carcinoma impede drug penetration. Cholesterol (+)‐liposomes act as membrane‐specific detergents, extracting cholesterol and reducing barrier function without cytotoxicity. Following endocytosis, cholesterol transfers from endosomes to liposomes and is metabolized in the ER.
Chansik Kim +9 more
wiley +1 more source
Extremely limited spatial and temporal utilization for wild Chinese alligator (<i>Alligator sinensis</i>). [PDF]
Li M +8 more
europepmc +1 more source
Targeting WDR12 Unleashes T‐Cell‐Mediated Antitumor Activity in Melanoma by Destabilizing CD276
WDR12 cooperates with the chaperonin subunit CCT7 to maintain CD276 stability on tumor cells, suppressing T‐cell activity and promoting immune escape. SU14813, a small‐molecule WDR12 inhibitor, reduces CD276 stability and relieves CD276‐mediated T‐cell suppression.
Jie Pan +10 more
wiley +1 more source
Abstract With the development of dental microwear texture analysis (DMTA), there has been an increasing application of DMTA for dietary estimation in extant and fossil reptiles, including dinosaurs. While numerous feeding experiments exist for herbivorous mammals, knowledge remains limited for carnivorous reptiles. This study aimed to qualitatively and
K. Usami, M. O. Kubo
wiley +1 more source
Carrier‐free self‐assembled nanomedicine for combination‐therapy of acute myeloid leukemia
CPDS combines drugs with three different mechanisms of action to achieve a multi‐mechanism combination therapy for AML by directly killing tumor cells and activating anti‐tumor immunity. Abstract As the main acute myeloid leukemia (AML) clinical treatment, the chemotherapy alone cannot meet the clinical therapeutic needs due to the high heterogeneity ...
Meihong Chai +14 more
wiley +1 more source
IUCN‐defined extant distribution of the Indo‐Pacific finless porpoise (Neophocaena phocaenoides), overlaid with occurrence records, global Marine Protected Areas (MPAs), and Important Marine Mammal Areas (IMMAs). ABSTRACT Prior to this study, the narrow‐ridged finless porpoise (Neophocaena asiaeorientalis) had been extensively studied across East Asia,
Manokaran Kamalakannan +7 more
wiley +1 more source
Genomic insights and the conservation potential of captive breeding: The case of Chinese alligator. [PDF]
Pan T +13 more
europepmc +1 more source
Fish Scales: A Multifunctional Biomaterial from Nature
Fish scales demonstrate nature's solution to impact protection through overlapping multilayered architecture. This biological design combines mineralized surfaces with collagen networks to achieve both flexibility and fracture resistance. The structural principles inspire advanced protective materials and biomedical implants, where damage tolerance ...
Liyao Dong, Xiaojie Sun, Xiguang Chen
wiley +1 more source

