Results 71 to 80 of about 1,679 (149)

Are China’s oldest-old living longer with less disability? A longitudinal modeling analysis of birth cohorts born 10 years apart

BMC Medicine, 2019
Background China has transitioned from being one of the fastest-growing populations to among the most rapidly aging countries worldwide. In particular, the population of oldest-old individuals, those aged 80+, is projected to quadruple by 2050.
Zuyun Liu, Ling Han, Qiushi Feng, Matthew E. Dupre, Danan Gu, Heather G. Allore, Thomas M. Gill, Collin F. Payne   +7 more
doaj   +1 more source

Sociodemographic, health-related, and social predictors of subjective well-being among Chinese oldest-old: a national community-based cohort study

BMC Geriatrics, 2021
Background There is still a lack of systematic investigation of comprehensive contextual factors of subjective well-being (SWB) among Chinese oldest-old.
Gang Cheng, Yan Yan
doaj   +1 more source

Saliva MicroAge: A salivary microbiome based machine learning model for noninvasive aging assessment and health state prediction

iMetaOmics, Volume 2, Issue 4, December 2025.
Saliva MicroAge is a machine learning‐based model designed to estimate biological age and assess health status using globally sourced salivary microbiome data. Trained on 4532 healthy samples, the model achieves high accuracy in predicting chronological age and captures health‐related deviations (MicroAgeGap) in various diseases.
Tiansong Xu, Yuting Niu, Chenyu Deng, Yoo Cheung, Yuman Li, Zhewen Hu, Shiyu Sun, Yiming Chen, Fan He, Gai Yang, Feng Chen, Chenggang Duan, Ying Huang, Xuliang Deng   +13 more
wiley   +1 more source

Single‐Cell and Spatial Multiomics: Applications for Diseases

MedComm, Volume 6, Issue 12, December 2025.
Schematic diagram of different single‐cell and spatial multiomics methods to describe the tissue layout of human diseases. ABSTRACT Complex and dynamic networks of molecules are involved in human diseases. ​Single‐cell and spatial multiomics approaches have created new avenues for understanding the pathogenesis and diagnosis of diseases.
Wentao Li, Chao Chen, Xin Zhu, Chenping Zhang   +3 more
wiley   +1 more source

Canonical Correlation Analysis on the Association Between Sleep Quality and Nutritional Status Among Centenarians in Hainan

Frontiers in Public Health, 2020
Objective: To analyze the correlation between nutritional status and sleep quality among centenarians.Methods: A total of 1,002 centenarians in Hainan were included in the full sample survey.
Guangdong Liu, Shanshan Yang, Wei Liu, Shengshu Wang, Penggang Tai, Fuyin Kou, Wangping Jia, Ke Han, Miao Liu, Yao He   +9 more
doaj   +1 more source

Longitudinal changes in cognitive function and its related factors in older type 1 diabetes mellitus patients without dementia

Journal of Diabetes Investigation, Volume 16, Issue 12, Page 2234-2241, December 2025.
The duration of T1DM was significantly associated with a decrease in the total MoCA‐J score over the 3 years after adjusting for age and sex. The age of onset of T1DM demonstrated a similar association. ABSTRACT Aims This study aimed to assess the longitudinal changes in cognitive function and associated factors in older patients with type 1 diabetes ...
Kaoru Nagasawa, Kimio Matsumura, Takayasu Uchida, Yuya Suzuki, Akihiro Nishimura, Yukifusa Igeta, Takashi Sakurai, Yasumichi Mori   +7 more
wiley   +1 more source

Genetic associations with longevity are on average stronger in females than in males

Heliyon
It is long observed that females tend to live longer than males in nearly every country. However, the underlying mechanism remains elusive. In this study, we discovered that genetic associations with longevity are on average stronger in females than in ...
Yi Zeng, Huashuai Chen, Xiaomin Liu, Zijun Song, Yao Yao, Xiaoyan Lei, Xiaozhen Lv, Lingguo Cheng, Zhihua Chen, Chen Bai, Zhaoxue Yin, Yuebin Lv, Jiehua Lu, Jianxin Li, Kenneth C. Land, Anatoliy Yashin, Angela M. O'Rand, Liang Sun, Ze Yang, Wei Tao, Jun Gu, William Gottschalk, Qihua Tan, Kaare Christensen, Therese Hesketh, Xiao-Li Tian, Huanming Yang, Viviana Egidi, Graziella Caselli, Jean-Marie Robine, Huali Wang, Xiaoming Shi, James W. Vaupel, Michael W. Lutz, Chao Nie, Junxia Min   +35 more
doaj   +1 more source

Is there an association between mild cognitive impairment and dietary pattern in chinese elderly? Results from a cross-sectional population study

BMC Public Health, 2010
Background Diet has an impact on cognitive function in most prior studies but its association with Mild Cognitive Impairment (MCI) in Chinese nonagenarians and centenarians has not been explored.
Wang Binyou, Wang Wenlei, Li Jun, Zeng Guo, Dong Birong, Wang Ziqi, Yuan Qiyuan   +6 more
doaj   +1 more source

How Do Different Forms of Note‐Taking Affect Second Language Vocabulary Learning?

Language Learning, Volume 75, Issue 4, Page 1185-1221, December 2025.
Abstract The present study compared learning gains at both form recall and meaning recall levels across three learning conditions: viewing without note‐taking, viewing with conventional note‐taking, and viewing with guided note‐taking. A total of 134 Chinese learners of English were assigned to three experimental groups and a no‐treatment control group.
Zhouhan Jin, Stuart Webb
wiley   +1 more source

G-395A polymorphism in the promoter region of the KLOTHO gene associates with frailty among the oldest-old

Scientific Reports, 2018
Frailty is characterized by a decline in physiological reserve and increased vulnerability. Previous studies have shown that KLOTHO (KL) plays a protective role in several age-related diseases. We hypothesize a probable protective effect of KL on frailty
Qiukui Hao, Yuting Wang, Xiang Ding, Biao Dong, Ming Yang, Birong Dong, Yuquan Wei   +6 more
doaj   +1 more source