Results 131 to 140 of about 131,127 (291)

Nanoformulated Diacerein Alleviates Hyperlipidemia via Gut Microbiota Modulation In Vivo

Nano Select, EarlyView.
A nanoformulation of diacerein (Nano‐DIA) was fabricated with carboxymethyl cellulose, achieving enhanced solubility and rapid dissolution for alternative anti‐hyperlipidemia therapeutics. Mechanistic studies revealed its in vivo lipid‐lowering efficacy is through metabolite‐mediated and microbiota‐dependent manner, highlighting its dual action on host
Zheng Peng, Yi Yu, Mingyi Chen, Weibin Wu, Chunyan Zhu, Caisheng Wu, Weihua Li, Zehua Liu, Qiang Xie   +8 more
wiley   +1 more source

Investigating Virus Clearance via pH Inactivation During Biomanufacturing [PDF]

, 2019
In the processing of biopharmaceuticals, viral clearance and viral safety are important for the development of monoclonal antibodies. Murine xenotropic leukemia virus (XMuLV) is one of the retroviruses, recommended by Food and Drug Administration (FDA ...
Xu, Wenbo
core   +2 more sources

Polyamine starvation causes accumulation of cadaverine and its derivatives in a polyamine-dependent strain of Chinese-hamster ovary cells [PDF]

, 1983
Erkki Hölttä, Pirkko Pohjanpelto
openalex   +1 more source

Induction and reparation of double-strand DNA breaks in V79 cells continuously exposed to low dose-rate Y-radiation [PDF]

Саратовский научно-медицинский журнал, 2013
Aim: to study the patterns of changes in the number of DNA double-strand breaks (DSB) in mammalian cells continuously exposed to low dose-rate y- radiation. Material and methods. Chinese hamster lung fibroblasts (V79) were used in this study.
Ozerov I.V., Bushmanov A.Yu., Anchishkina N.A., Guryev D.V., Pustovalova M.V., Smetanina N.M., Arkhangelskaya E.Yu., Vorobyova N.Y., Osipov A.N.   +8 more
doaj  

Adipose Tissue in SARS‐CoV‐2 Viral Tropism, Viral Replication, and the Concept of a Viral Reservoir: An Update

Obesity, EarlyView.
Adipose tissue as a potential reservoir for and modifier of SARS‐CoV‐2 infection and its complications. Schematic demonstrating the differences in subcutaneous and visceral adipose tissue and infection capacity of SARS‐CoV‐2 with interplay between macrophages and adipocytes as target cells for viral tropism.
Liam Charles Maher, Paul M. Ryan, Noel M. Caplice   +2 more
wiley   +1 more source

Precision mRNA Delivery via Ultrasound‐Controlled Release Perfluorocarbon Emulsions: An Innovative Ultrasound Theranostic Strategy with 19F MRI Feasibility

Small, EarlyView.
A key challenge in advancing messenger RNA (mRNA) therapeutics in cardiovascular diseases lies in achieving controlled release at the precise site within the vasculature. This study presents the development of perfluorocarbon nanodroplets with exceptional theranostic potential, enabling real‐time tracking through ultrasound and fluorine‐19 (19F ...
Haikun Liu, Mark Louis P. Vidallon, Yuyang Song, Aidan P. G. Walsh, Henry Gordon, Shulei Ren, Pengkai Shi, Bangyan Xu, Mitchell J. Moon, Sylvain Trépout, Rico F. Tabor, Alexis I. Bishop, Ulrich Flögel, Karlheinz Peter, Xiaowei Wang   +14 more
wiley   +1 more source

Preclinical Toxicity Screening of Sodium Dodecanoyloxybenzenesulfonate (LOBS) as a New Alternative Biocide Using In Vitro and In Vivo Models

Environmental Toxicology, EarlyView.
ABSTRACT Sodium hypochlorite is a well‐established biocide extensively used in both living and industrial environments; however, exposure to it or improper handling can harm the human body and the environment. Thus, safer alternatives to sodium hypochlorite are required.
Seung Eui Min, Seunghee Oh, Min Seong Jang, Kang‐Hyun Han   +3 more
wiley   +1 more source

Advances in Serum-Free Suspension Culture Technology for Animal Cells and Their Applications

Vaccines
Serum-free suspension culture technology for animal cells involves the division and proliferation of cells in serum-free medium as single cells or cell clusters within shaking flasks or bioreactors.
Wenna Ji, Ziyi Chen, Jinyu Zhou, Xinyu Yue, Zilin Qiao, Jiamin Wang   +5 more
doaj   +1 more source

Effect of Social Rank on Gut Microbes and Their Metabolites of Greater Long‐Tailed Hamsters (Tscherskia triton)

Integrative Zoology, EarlyView.
Social rank in greater long‐tailed hamsters (Tscherskia triton) shapes gut microbiota composition and metabolite profiles. Dominant males exhibit a “high‐vigilance, metabolically activated” phenotype, with elevated aggression and specific gut microbiota enriched in energy‐harvesting taxa and fecal queuine.
Da Zhang, Xiaoming Xu, Zhibin Zhang
wiley   +1 more source

Cyotoxicity of Etidronate as an Endodontic Chelator Against Periodontal Ligament Fibroblast

Australian Endodontic Journal, EarlyView.
ABSTRACT Etidronic acid (HEBP) causes fewer alterations in dentine and can be used mixed with sodium hypochlorite during root canal preparation. This study investigated the cytotoxicity effects of the HEDP and EDTA on human periodontal ligament fibroblast cells. Primary culture was established from human periodontal ligament tissue of one donor and was
Bruno Vila Nova de Almeida, Patrícia de Almeida Rodrigues, Geovanni Pereira Mitre, Maria Sueli da Silva Kataoka, João de Jesus Viana Pinheiro, Talita Tartari, Oscar Faciola Pessoa   +6 more
wiley   +1 more source