Results 261 to 270 of about 131,127 (291)
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Cricetulus griseus (Chinese hamster)
1967The long arm of the X may show a weak secondary constriction at the distal third. However, without autoradiography with tritiated thymidine, the X may be indistinguishable from chromosomes No. 4. The Y chromosome is morphologically unique.
T. C. Hsu, Kurt Benirschke
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Heterogeneity in Chinese hamster ribosomal DNA
Chromosoma, 1978A discrete heterogeneity has been detected in Chinese hamster ribosomal DNA after Eco R1 digestion of total DNA followed by a Southern transfer and hybridization with [125I]18S or [125I]28S ribosomal RNA. Digestion with Eco R1 produces three fragments, 4.3, 6.0 and 9.5 x 10(6) daltons respectively, which hybridize with 18S RNA.
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Chinese hamsters and diabetes mellitus
Acta Diabetologica Latina, 1964In the Chinese Hamster inbreeding and exposure to stressful situations are capable of precipitating Diabetes mellitus. The condition produced by gene-mutation is hereditary and the signs and symptoms of the disease, including degenerative vascular lesions, resemble closely those observed in human subjects.
Anna Sirek, Otakar V. Sirek
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Characterization of multiple Chinese hamster carbonyl reductases
Chemico-Biological Interactions, 2001Carbonyl reductase (CR) is an enzyme which can catalyze the oxidoreduction of various carbonyl compounds in the presence of NAD(P)H. With the PCR method, using primers carrying the conserved nucleotide sequence among mammalian CRs, we isolated three different cDNAs (CHCR1, CHCR2 and CHCR3) which encode a unique carbonyl reductase from the Chinese ...
T, Terada +8 more
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Pachytene chromomere maps of Chinese hamster autosomes
Cytogenetic and Genome Research, 1981A standard chromomere map of the Chinese hamster autosomes at pachytene has been prepared and presented. Comparison of bands on somatic chromosomes and chromomeres on meiotic chromosomes revealed a close correspondence between the two. Chromosome contraction from prophase to metaphase at mitosis and early to late pachytene at meiosis lead, due to ...
S C, Jhanwar, R S, Chaganti
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A scaffold for the Chinese hamster genome
Biotechnology and Bioengineering, 2007AbstractChinese hamster ovary (CHO) cells are a prevalent tool in biological research and are among the most widely used host cell lines for production of recombinant therapeutic proteins. While research in other organisms has been revolutionized through the development of DNA sequence‐based tools, the lack of comparable genomic resources for the ...
Katie F, Wlaschin, Wei-Shou, Hu
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Metabolomics of Chinese Hamster Ovary Cells
Increasing demand of protein biotherapeutics produced using Chinese hamster ovary (CHO) cell lines necessitates improvement in the production yield of the bioprocess. Various cell engineering, improved media formulation and process-design based approaches utilizing the power of OMICS technologies, specifically, genomics and proteomics, have been ...Rita, Singh +5 more
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CHINESE HAMSTER OVARY CELL LINE
2012The present invention is related to a Chinese hamster ovary cell line as deposited with the European Collection of Cell Cultures (ECACC) under accession number 10090201; use of the cell line for the production of a recombinant polypeptide; a kit comprising the cell line; and methods for the production of recombinant polypeptide.
HATTON DIANE +4 more
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Pesticide clastogenicity in Chinese hamster ovary cells
Mutation Research/Genetic Toxicology, 1987Paraquat, alachlor, butachlor, phorate and monocrotophos, several of the most extensively used pesticides in Taiwan, were investigated for their clastogenicity using chromosome aberration (CAb) induction in Chinese hamster ovary (CHO) cells. Significance levels of the binomial trend analysis and binomial mutagenicity data test were two criteria for the
M F, Lin, C L, Wu, T C, Wang
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Dolichol metabolism in Chinese hamster ovary cells
Biochemistry and Cell Biology, 1992The addition of oligosaccharide to asparagine residues of soluble and membrane-associated proteins in eukaryotic cells involves a polyisoprenoid lipid carrier, dolichol. In Chinese hamster ovary cells, the major isomer of this polyisoprenol has 19 isoprenyl units, the terminal one being saturated.
A, Kaiden, S S, Krag
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