Results 271 to 280 of about 339,190 (282)

Plasminogen with type‐I mutation in the Chinese Han population

Clinical Genetics, 1994
A functionally inactive plasminogen (PLG) variant, PLG M5, is polymorphic in the Japanese population and has a codon 601 mis‐sense mutation (GCT for Ala to ACT for Thr), designated type‐I mutation. The present study aimed to reveal whether the plasminogen with type‐I mutation is present in the Chinese Han population. Among 104 healthy Chinese students,
L, Li, S, Kikuchi, T, Arinami, K, Kobayashi, S, Tsuchiya, H, Hamaguchi   +5 more
openaire   +2 more sources

Developmental regulation of CYP3A4 and CYP3A7 in Chinese Han population

Drug Metabolism and Pharmacokinetics, 2016
CYP3A4 and CYP3A7 are generally served as the major adult and fetal liver forms, respectively, and exhibited a developmental switch during liver maturation. The objective of this study was to explore the potential mechanisms associated with the developmental switch of CYP3A4 and CYP3A7 in the Chinese Han population.
Hang He, Ya-Li Nie, Jiang-Feng Li, Xiang-Guang Meng, Wei-Hong Yang, Yu-Long Chen, Shu-Jie Wang, Xiaochao Ma, Quan-Cheng Kan, Li-Rong Zhang   +9 more
openaire   +2 more sources

Positive association between NTNG1 and schizophrenia in Chinese Han population

Journal of Genetics, 2011
1Department of Psychiatry, First Affiliated Hospital, China Medical University, Nanjing North Street, Shenyang 110001, People’s Republic of China 2Shenyang Pharmaceutical University, Whenhua Road, Shenyang 110001, People’s Republic of China 3BenXi Mental Hospital, Digong Road, Benxi 117000, People’s Republic of China 4Dalian Seventh People’s Hospital ...
Yuzhang, Zhu, Huan, Yang, Yuxia, Bi, Ying, Zhang, Chao, Zhen, Shoufu, Xie, Heping, Qin, Jia, He, Li, Liu, Ying, Liu   +9 more
openaire   +2 more sources

Genetic Determinants of Warfarin Dosing in the Han-Chinese Population

Pharmacogenomics, 2009
Warfarin, a widely prescribed oral anticoagulant, is used for the prevention of thromboembolism. Polymorphisms in CYP2C9 and VKORC1 have been shown to be associated with warfarin dose requirements. However, it is likely that other genes could also affect warfarin dose.In this study, we aimed to identify additional genes influencing warfarin dosing in ...
M T Michael, Lee, Chien-Hsiun, Chen, Ching-Heng, Chou, Liang-Suei, Lu, Hui-Ping, Chuang, Ying-Ting, Chen, Amir N, Saleem, Ming-Shien, Wen, Jin-Jer, Chen, Jer-Yuarn, Wu, Yuan-Tsong, Chen   +10 more
openaire   +3 more sources

Identification of common variants within KCNK17 in Chinese Han population

Journal of Huazhong University of Science and Technology [Medical Sciences], 2010
KCNK17 is a member of the acid-sensitive subfamily of tandem pore K(+) channels, which are open at all membrane potentials an red contribute to cellular resting membrane potential. Recent genome-wide study (GWA) has shown that variants within KCNK17 confer genetic susceptibility for increasing ischemic stroke.
Zhouping, Tang, Hu, Ding, Yujun, Xu, Shabei, Xu   +3 more
openaire   +2 more sources

Population Data of 15 STR in Chinese Han Population From North of Guangdong

Journal of Forensic Sciences, 2005
Abstract The samples were obtained from 102 unrelated, healthy individuals of Chinese Han population living in north of Guangdong province of China. Genomic DNA was extracted using the Chelex100 protocol as described by Walsh et al. (1).
Jun, Zhu, Jingfeng, Li, Yanxia, Guo, Kaihui, Liu, Bofeng, Zhu, Yao, Liu   +5 more
openaire   +2 more sources

ADA Polymorphisms and Asthma: A Study in the Chinese Han Population

Journal of Asthma, 2006
We have studied a sample of 120 asthmatic patients and 116 healthy control subjects from the Chinese Han population. Three polymorphic sites: ADA(1), ADA(2), and ADA(6), within the ADA gene have been examined. The proportion of carriers of *2 allele at locus ADA(1) is drastically reduced in asthmatics as compared to controls.
Liu, Y, Qi, H, Wu, HC, Zhao, F, Dai, Y, SACCUCCI, PATRIZIA, BOTTINI, NUNZIO, GLORIA, FULVIA   +7 more
openaire   +4 more sources

Common Single Nucleotide Polymorphisms and Keratoconus in the Han Chinese Population

Ophthalmic Genetics, 2013
To investigate whether the tag single nucleotide polymorphisms (tSNPs) in VSX1, COL4A3, COL4A4, IL1A and IL1B genes were associated with keratoconus (KTCN) in the Han Chinese population.Ninety-seven KTCN patients and 101 healthy controls were enrolled in this study. All cases were diagnosed on the basis of clinical examination.
Yani, Wang, Tianbo, Jin, Xuehui, Zhang, Wei, Wei, Yan, Cui, Tingting, Geng, Qianping, Liu, Jing, Gao, Ming, Liu, Chao, Chen, Changning, Zhang, Xiuping, Zhu   +11 more
openaire   +2 more sources

ACP1 Genotype and Asthma in the Chinese Han Population

International Archives of Allergy and Immunology, 2005
Liu, YG, Wu, CG, SACCUCCI, PATRIZIA, GLORIA, FULVIA   +3 more
openaire   +4 more sources

Whole genome sequencing of (CHS) Southern Han Chinese population HapMap population

2010
The purpose of the project is to support the discovery and understanding of genetic variants that influence human disease. DNA for this sample was extracted from lymphoblastoid cell line.
openaire   +1 more source