Results 301 to 310 of about 771,775 (343)

Polymorphism of DEFA in Chinese Han population with IgA nephropathy

Human Genetics, 2014
Our recent genome-wide association study (GWAS) had discovered a new locus at 8p23 (rs2738048) associated with IgA nephropathy (IgAN) in Chinese Han patients, implicating the DEFA gene family within this locus as susceptibility genes. However, it is still unknown whether there are additional variations within these genes associated with the disease ...
Ricong, Xu, Shaozhen, Feng, Zhijian, Li, Yonggui, Fu, Peiran, Yin, Zhen, Ai, Wenting, Liu, Xueqing, Yu, Ming, Li   +8 more
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Novel mutations found in mitochondrial diabetes in Chinese Han population

Diabetes Research and Clinical Practice, 2007
Mitochondria provide cells with most of the energy in the form of ATP. Mutations in mitochondrial DNA (mtDNA) are associated with type 2 diabetes mellitus (T2DM) because ATP plays a critical role in the production and the release of insulin. To systematically determine mutant loci and to investigate their association with T2DM in Chinese Han population,
Song-Mei, Liu, Xin, Zhou, Fang, Zheng, Xia, Li, Fang, Liu, Hong-Mei, Zhang, Yan, Xie   +6 more
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Analysis of HLA‐DM polymorphisms in the Chinese Han population

Tissue Antigens, 2012
Non‐classical human leukocyte antigen (HLA)‐DM plays an important and unique role in the processing and presentation of exogenous antigens. Polymorphisms of certain genes and frequency of alleles in populations may indicate susceptibility to certain diseases.
M L, Feng, R Z, Liu, T, Shen, Y L, Zhao, Z Y, Zhu, D Z, Liu   +5 more
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AMPD1 functional variants associated with autism in Han Chinese population

European Archives of Psychiatry and Clinical Neuroscience, 2014
Autism is a childhood neurodevelopmental disorder with high heterogeneity. Following our genome-wide associated loci with autism, we performed sequencing analysis of the coding regions, UTR and flanking splice junctions of AMPD1 in 830 Chinese autism individuals as well as 514 unrelated normal controls.
Lusi, Zhang, Jianjun, Ou, Xiaojuan, Xu, Yu, Peng, Hui, Guo, Yongcheng, Pan, Jingjing, Chen, Tianyun, Wang, Hao, Peng, Qiong, Liu, Di, Tian, Qian, Pan, Xiaobin, Zou, Jingping, Zhao, Zhengmao, Hu, Kun, Xia   +15 more
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Plasminogen with type‐I mutation in the Chinese Han population

Clinical Genetics, 1994
A functionally inactive plasminogen (PLG) variant, PLG M5, is polymorphic in the Japanese population and has a codon 601 mis‐sense mutation (GCT for Ala to ACT for Thr), designated type‐I mutation. The present study aimed to reveal whether the plasminogen with type‐I mutation is present in the Chinese Han population. Among 104 healthy Chinese students,
L, Li, S, Kikuchi, T, Arinami, K, Kobayashi, S, Tsuchiya, H, Hamaguchi   +5 more
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Positive association between NTNG1 and schizophrenia in Chinese Han population

Journal of Genetics, 2011
1Department of Psychiatry, First Affiliated Hospital, China Medical University, Nanjing North Street, Shenyang 110001, People’s Republic of China 2Shenyang Pharmaceutical University, Whenhua Road, Shenyang 110001, People’s Republic of China 3BenXi Mental Hospital, Digong Road, Benxi 117000, People’s Republic of China 4Dalian Seventh People’s Hospital ...
Yuzhang, Zhu, Huan, Yang, Yuxia, Bi, Ying, Zhang, Chao, Zhen, Shoufu, Xie, Heping, Qin, Jia, He, Li, Liu, Ying, Liu   +9 more
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Genetic Determinants of Warfarin Dosing in the Han-Chinese Population

Pharmacogenomics, 2009
Warfarin, a widely prescribed oral anticoagulant, is used for the prevention of thromboembolism. Polymorphisms in CYP2C9 and VKORC1 have been shown to be associated with warfarin dose requirements. However, it is likely that other genes could also affect warfarin dose.In this study, we aimed to identify additional genes influencing warfarin dosing in ...
M T Michael, Lee, Chien-Hsiun, Chen, Ching-Heng, Chou, Liang-Suei, Lu, Hui-Ping, Chuang, Ying-Ting, Chen, Amir N, Saleem, Ming-Shien, Wen, Jin-Jer, Chen, Jer-Yuarn, Wu, Yuan-Tsong, Chen   +10 more
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Identification of common variants within KCNK17 in Chinese Han population

Journal of Huazhong University of Science and Technology [Medical Sciences], 2010
KCNK17 is a member of the acid-sensitive subfamily of tandem pore K(+) channels, which are open at all membrane potentials an red contribute to cellular resting membrane potential. Recent genome-wide study (GWA) has shown that variants within KCNK17 confer genetic susceptibility for increasing ischemic stroke.
Zhouping, Tang, Hu, Ding, Yujun, Xu, Shabei, Xu   +3 more
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Population Data of 15 STR in Chinese Han Population From North of Guangdong

Journal of Forensic Sciences, 2005
Abstract The samples were obtained from 102 unrelated, healthy individuals of Chinese Han population living in north of Guangdong province of China. Genomic DNA was extracted using the Chelex100 protocol as described by Walsh et al. (1).
Jun, Zhu, Jingfeng, Li, Yanxia, Guo, Kaihui, Liu, Bofeng, Zhu, Yao, Liu   +5 more
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ADA Polymorphisms and Asthma: A Study in the Chinese Han Population

Journal of Asthma, 2006
We have studied a sample of 120 asthmatic patients and 116 healthy control subjects from the Chinese Han population. Three polymorphic sites: ADA(1), ADA(2), and ADA(6), within the ADA gene have been examined. The proportion of carriers of *2 allele at locus ADA(1) is drastically reduced in asthmatics as compared to controls.
Liu, Y, Qi, H, Wu, HC, Zhao, F, Dai, Y, SACCUCCI, PATRIZIA, BOTTINI, NUNZIO, GLORIA, FULVIA   +7 more
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