Results 41 to 50 of about 4,023,063 (284)

Deep sequencing of plant and animal DNA contained within traditional Chinese medicines reveals legality issues and health safety concerns [PDF]

, 2012
Traditional Chinese medicine (TCM) has been practiced for thousands of years, but only within the last few decades has its use become more widespread outside of Asia. Concerns continue to be raised about the efficacy, legality, and safety of many popular
Michael Bunce, Haile, James, Jayne Houston, Haile James, White Nicole E., Bellgard, Matthew I., Megan L Coghlan, Paula Moolhuijzen (171379), Paula Moolhuijzen, Dáithí C. Murray (171368), Bellgard, M.I., Houston Jayne, Murray, D.C., Houston, Jayne, Dáithí C Murray, White, N.E., Coghlan, Megan L., James Haile (40135), Jayne Houston (171362), Coghlan, Megan, Bellgard Matthew I., Coghlan Megan L., Matthew I. Bellgard (171383), Coghlan, M.L., Matthew I Bellgard, Murray Dáithí C., Moolhuijzen, Paula, Megan L. Coghlan (171354), White, Nicole E., Nicole E. White (171373), Moolhuijzen, P., Haile, J., White, Nicole, Houston, J., Bellgard, M., Moolhuijzen Paula, Murray, D., Michael Bunce (31164), James Haile, Murray, Dáithí C., Nicole E White, Bunce, M., Bunce Michael, Bunce, Michael   +43 more
core   +2 more sources

Coixenolide Enhances Antitumor Immunity of Cytotoxic CD8+ T Cells by Inhibiting S100A8/A9‐CD36 Axis in Obesity‐Associated Pancreatic Adenocarcinoma

Advanced Science, EarlyView.
Pancreatic adenocarcinoma (PAAD) remains highly lethal with limited treatment options. This study demonstrates that coixenolide, a bioactive compound from Coix lacryma‐jobi L. and a key component of the clinically approved Kanglaite injection, exhibits enhanced antitumor efficacy in high‐fat diet (HFD)‐induced obese mice bearing PAAD tumors compared to
Kaidi Chen, Rong Chen, Wei Li, Bin Song, Ruiying Zhang, Lewei Dai, Yuwei Qi, Ruqian Chen, Yifan Xu, Hangbin Li, Jingyi Huang, Fangping Wu, Jianan Peng, Xinyu Wang, Yang Xiong, Chaofeng Mu, Guilin Cheng, Zhaoshen Li, Shanming Ruan, Lei Huang, Mancang Gu   +20 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Innovative Test Strip‐Based Colorimetric Sensors Integrated With Affinity Chromatography: Acetylcholinesterase Inhibitor Screening Breakthrough in Lycium Barbarum Leaves

Advanced Science, EarlyView.
Schematic diagrams illustrating the breakthrough in the screening of AChE inhibitors from LBL, and the research process of the pharmacodynamics of the NCP are presented. ABSTRACT Current Alzheimer's drugs exhibit limited effectiveness, highlighting the necessity for multi‐target treatments.
Yuping Sa, Hui Yuan, Jingui Ma, Zhigang Yang, Mei Wang, Weibiao Wang, Lingling Yang, Fen Ma, Weiman Zhang, Gidion Wilson Mening'oo, Guoning Chen, Xueqin Ma   +11 more
wiley   +1 more source

Research progress on application of Chinese herbal additives in ruminant production

Siliao yanjiu, 2023
Chinese herbs are rich in protein, vitamins, flavonoids, organic acids and other nutrients. Chinese herbal medicine can promote the growth and development of animals, improve the immunity of the body, and have significant effect on anti-stress and ...
QIN Xing, MENG Jia-hao, WANG Zhi-fang, ZHANG Xia, YANG Xin-ping, ZHANG Yun-sheng, DAI Jin-ping   +6 more
doaj  

Rhoifolin Alleviates Ulcerative Colitis by Targeting NMNAT1 and Activating SIRT1‐FOXO1 Signaling to Enhance ILC3s Effector Function

Advanced Science, EarlyView.
Rhoifolin directly targets NMNAT1, thereby activating nicotinamide salvage pathway and promoting intracellular NAD+ biosynthesis. Elevated NAD+ levels enhance SIRT1 activity, leading to FOXO1 deacetylation and nuclear translocation. Nuclear FOXO1 subsequently binds to the IL‐22 promoter, upregulating IL‐22 transcription and potentiating ILC3 effector ...
Hongqiong Yang, Yishu Zhang, Sijia Feng, Xiaoqing Ma, Jiayi Feng, Junwei Wang, Jialin Gao, An Pan, Dapeng Wu, Kang Ding, Caijuan Zheng, Qi Lv, Lihong Hu   +12 more
wiley   +1 more source

Research progress on application of Chinese herbal medicine feed additives in sow production

Siliao yanjiu, 2022
Chinese herbal medicine is a safe, green and efficient feed additive, which can supplement the body's nutrients, regulate reproductive hormone secretion, promote reproductive organ development, enhance immunity, improve sow physique and improve the ...
ZHOU Peng, SONG Chen, CHI Shi-hong, FENG Jun   +3 more
doaj  

Senkyunolide I Inhibits mtDNA‐cGAS‐STING Signaling in Macrophages via Targeting VDAC1 Oligomerization to Attenuate Ulcerative Colitis

Advanced Science, EarlyView.
In macrophages, senkyunolide I (SEI) directly targets the K12 residue of VDAC1 to inhibit its stress‐induced oligomerization, a critical upstream event that effectively prevents mitochondrial DNA release and subsequent cGAS‐STING pathway activation.
Zhiming Ye, Yihang Huang, Bohao Han, Lei Zhang, Can Yu, Yang Yang, Bing Liu, Yongping Jian, Zhixiang Xu, Cheng Zeng   +9 more
wiley   +1 more source

Chinese herbal therapy and Western drug use, belief and adherence for hypertension management in the rural areas of Heilongjiang province, China. [PDF]

PLoS ONE, 2015
Traditional Chinese medicine (TCM) including Chinese herbal therapy has been widely practiced in China. However, little is known about Chinese herbal therapy use for hypertension management, which is one of the most prevalent chronic conditions in China.
Xia Li, Mingkai Peng, Yuan Li, Zheng Kang, Yanhua Hao, Hong Sun, Lijun Gao, Mingli Jiao, Qunhong Wu, Hude Quan   +9 more
doaj   +1 more source

Carrier‐Free Berberine/Nitidine Chloride Self‐Assembled Nanoparticles Induce Ferroptosis to Overcome Bortezomib Resistance in Multiple Myeloma

Advanced Science, EarlyView.
A schematic illustrating the fabrication process and ferroptosis‐mediated therapeutic mechanism of carrier‐free self‐assembled BBR/NC‐SAPs for overcoming bortezomib resistance in multiple myeloma. ABSTRACT Therapeutic relapse driven by bortezomib resistance represents a formidable clinical barrier in the management of multiple myeloma (MM).
Yiwen Lv, Shuang Liu, Hong Wu, Guiluan Li, Ying Rong, Guangchao Li, Yangmin Zhu, Qi Zhong, Ruiming Ou, Huijuan Shen, Zhi Liu, Jing Huang, Zhenwei Wang, Pei Lin, Qing Zhang, Guopan Yu, Zhao Yin   +16 more
wiley   +1 more source