Results 51 to 60 of about 4,023,063 (284)

CDK4/MERCs/PINK1 Axis Drives PFOA/HFPO‐TA‐Induced Cardiac Senescence via Mitophagy Defect and cGAS‐STING Activation: In Vitro Amelioration by Cycloastragenol

Advanced Science, EarlyView.
The present study demonstrated that PFOA and HFPO‐TA exposure suppressed CDK4, disrupted MERCs and impaired PINK1/Parkin‐mediated mitophagy, thereby accelerating cardiac senescence, whereas CAG effectively reversed these pathological changes in vitro. Our findings identify CDK4 as a critical regulator bridging mitophagy defects and cardiac senescence ...
Nuo‐Wa Li, Jun‐Ze Jiang, Ying‐Ying Liu, Tian‐Tian Zhang, Kanwar Kumar Malhi, Xin Yao, Jin‐Long Li   +6 more
wiley   +1 more source

Research progress of traditional Chinese medicine on control of piglet diarrhea

Siliao yanjiu, 2021
Piglet diarrhea is a common multi-factor disease in pig industry, and it is also one of the most serious piglet diseases at present. Traditional Chinese medicine has many advantages, such as extensive resources, easy to absorb, not easy to develop drug ...
Tao LI, Hong-yu RAO, Yong-gang WANG
doaj  

Targeting β2‐Adrenergic Receptor Stability With Lycorine Reveals a Host‐Directed Pathway for Antiviral Defense Against Poxviruses

Advanced Science, EarlyView.
Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang, Shuqin Xu, Zixuan Zhang, Chenwen Wan, Xiaoqin Wang, Peihua Wang, Huini Yang, Tianxiao Huang, Yijia Yuan, Faiza Atique, Rui Yang, Yingli He, Zhijun Liu   +12 more
wiley   +1 more source

Buyer beware? : does the information provided with herbal products available over the counter enable safe use? [PDF]

, 2011
Background: Herbal products obtained over the counter are commonly used in Europe, North America and Australia. Although there is concern about a lack of information provided to consumers to allow the safe use of these products, there has been no ...
Nicolson Donald J, Knapp, Peter, Knapp Peter, Raynor David K, Rebecca Dickinson, Nicolson, Donald J., Dickinson Rebecca, Peter Knapp, Raynor, David K., Dickinson, R, Donald J Nicolson, David K Raynor, Raynor, DK, Long Andrew F, Knapp, P, Long, AF, Andrew F Long, Long, Andrew F., Dickinson, Rebecca, Nicolson, DJ   +19 more
core   +2 more sources

Corynoxine Inhibits Tumor Growth via Targeting NQO1 and Modulating the PTPA–NQO1/PP2A Switch to Activate PP2A

Advanced Science, EarlyView.
Corynoxine exerts potent broad‐spectrum anticancer activity by directly targeting NQO1. This interaction dissociates the oncogenic NQO1‐PTPA complex, releasing PTPA to robustly activate the tumor suppressor PP2A. Consequently, downstream Raf/MEK/ERK and PI3K/AKT signaling pathways are suppressed, downregulating c‐Myc and driving tumor regression ...
Guoqing Hou, Li Lin, Mengjie Xia, Ruohan Liang, Yueyue Zhang, Linna Du, Xuan Cao   +6 more
wiley   +1 more source

Progress in application of Chinese herbal medicine additives in sows production

Siliao yanjiu, 2023
Chinese herbal medicine has a wide range of sources, convenient materials, low residue, no drug resistance and other characteristics, and has a wide application prospect in livestock and poultry production.
LI Ping, MO Yu-peng, SU Zhi-wei, MA Zhong-hui   +3 more
doaj  

Modalities of Chinese medicine

, 2016
Chinese medicine uses a number of modalities or therapies for both prevention and treatment of disease. There are two main categories of treatment modalities: herbal and manual treatment. Many medicinal herbs are usually used in combination.
Xue, Charlie C. L., O’Brien, Kylie A. (R14413)   +1 more
core   +1 more source

A Huaxian Formula Nanoformulation Confers Protection Against Acute Radiation‐Induced Lung Injury by Targeting Ferroptosis

Advanced Science, EarlyView.
An inhalable, nanoengineered herbal therapy achieves protection against acute radiation‐induced lung injury via self‐assembled nanomicelle‐mediated pulmonary targeting and a previously unrecognized dual mechanism that attenuates oxidative stress while inhibiting ferroptosis in alveolar epithelial cells.
Li Quan, Junyang Chen, Xingmin Chen, Zengyi Fang, Yuanzhen Mi, Pingjin Zou, Shunlian Fu, Huakang Li, Ke Xu, Bing Lin, Jinyi Lang, Meihua Chen   +11 more
wiley   +1 more source

Effect of compound Chinese herbal medicine additives on fat deposition and lipid metabolism in green-eggshell laying hens

Siliao yanjiu, 2021
The experiment studied the effect of different doses of compound Chinese herbal medicine additives on fat deposition and lipid metabolism in green-eggshell laying hens.
Jie-rui ZHOU, Yuan-yuan LI, Shi-jie LU, Hong-mei LI, Fu-guang XUE, Nai-xia WU, Hong-xiang WU   +6 more
doaj  

Beyond Conventional: A Review of Phytochemical‐Hydrogel Systems Enhanced by AI and 3D Printing for Chronic Wound Management

Advanced Science, EarlyView.
This review systematically bridges chronic wound pathology with natural phytochemical hydrogel therapeutics. A pathology‐to‐phytochemical mechanistic mapping framework is established, linking specific wound hallmarks to targeted phytochemical interventions.
Yitao Zhou, Xing Liu, Cuiyi Wang, Xiaoxuan Zhao, Pengrun Zhang, Jingjing Gu, Qiuhua Sun, Malcolm Xing, Yeqin Yang   +8 more
wiley   +1 more source