Results 121 to 130 of about 1,545,827 (298)

Cross‐Regulation Between DNA Methylation and Circadian Clock Reprogramming in Ovarian Cancer: Mechanistic Insights, Biomarker Potential, and Therapeutic Implications

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Early diagnosis remains challenging, recurrence rates remain high, and platinum resistance frequently develops in ovarian cancer (OC), collectively representing major barriers to long‐term patient survival. DNA methylation (DNAm), as a relatively stable yet dynamically modifiable epigenetic signature, can capture alterations in tumor states ...
Min Xing   +6 more
wiley   +1 more source

Hormone therapy (HT) in women with premature ovarian insufficiency or early menopause: Time to think of a new paradigm for healthy aging. A joint FIGO and IMS position paper

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Premature ovarian insufficiency (POI) and early menopause (EM) affect millions of women worldwide. Compared with normal menopause, they confer a longer duration of estrogen deficiency and are associated not only with a shorter lifespan, but with a reduced healthspan, owing to an increased risk of cardiovascular, skeletal, cognitive and ...
Chiara Benedetto   +8 more
wiley   +1 more source

Genome‐Wide Analysis of the APETALA2/Ethylene‐Responsive Factor Gene Family in Carthamus tinctorius L.

open access: yesPlant Direct
The APETALA2/ethylene‐responsive factor (AP2/ERF) superfamily represents a class of transcription factors involved in plant growth, development, and stress responses.
Zheng‐Wei Tan   +8 more
doaj   +1 more source

Are herbal medicines effective in the treatment of ischemic stroke? : a systematic review of human-controlled clinical trials

open access: yes, 2019
Cerebrovascular diseases are common, and stroke constitutes the third cause of death as well as the first cause of disability all over the world. Many studies have demonstrated the beneficial effects of herbal preparations on stroke.
Javan, Roghayeh   +7 more
core   +1 more source

Gut Enterococcus faecium derived leucic acid mediates the antiobesity effect of dietary fiber

open access: yesiMeta, EarlyView.
This study identified Enterococcus faecium as a gut bacterium with anti‐obesity activity, which alleviated adipocyte hypertrophy, dyslipidemia, and hepatic steatosis by converting leucine into leucic acid (LEA) to regulate mitochondrial oxidative phosphorylation.
Baifei Hu   +9 more
wiley   +1 more source

Dynamic changes of major non-volatile components during Gongfu black tea processing

open access: yesShipin yu jixie
ObjectiveTo investigate the dynamic changes in the major non-volatile chemical components during the processing of Jianghua Kucha 21-3 Gongfu black tea.MethodsFresh one-bud-two-leaf autumn tea leaves of Jianghua Kucha 21-3 were used as raw materials ...
Deng Ming   +6 more
doaj   +1 more source

Chinese herbal medicines for hypercholesterolemia (Protocol)

open access: yes, 2010
This is the protocol for a review and there is no abstract.
Jian Liu (33711)   +2 more
core  

Spatiotemporal Pattern Evolution and Driving Mechanisms of World Botanical Gardens Over Five Centuries

open access: yesIntegrative Conservation, EarlyView.
This study presents a comprehensive review of the 500‐year spatiotemporal evolution of global botanical gardens, identifying three major development stages—initial exploration (1543–1699), steady expansion (1700–1899), and rapid proliferation (1900–2020)—with six distinct sub‐stages. We propose a tripartite driving framework grounded in colonial botany
Shidong Li, Guangzhen Shi, Qingwei Li
wiley   +1 more source

Chinese Herbal Medicines [PDF]

open access: yesJournal of Medical Biography, 2003
openaire   +1 more source

Traditional Chinese Medicine and Natural Products Targeting Right Ventricular Dysfunction in Pulmonary Arterial Hypertension: Toward Precision Cardiometabolic Therapy

open access: yesiNew Medicine, EarlyView.
Natural products and traditional Chinese medicine target metabolic pathways underlying right ventricular dysfunction in pulmonary arterial hypertension. Integrating multi‐omics, artificial intelligence, and systems biology may enable precision cardiometabolic therapies to restore right ventricular metabolism and improve clinical outcomes.
Yihao Wu, Zhehui Tang, Hongwei Yao
wiley   +1 more source

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