Results 131 to 140 of about 1,545,827 (298)

Polydatin Alleviates APAP‐Induced Hepatotoxicity by Targeting C/EBPβ to Suppress the NLRP3 Inflammasome Signaling Pathway

iNew Medicine, EarlyView.
PD alleviates APAP‐induced ALI by inhibiting the NLRP3 inflammasome signaling pathway. C/EBPβ is identified as a direct target via multimethod validation. PD promotes the deacetylation of C/EBPβ via Sirt1. The Sirt1/C/EBPβ/NLRP3 signaling axis is defined for PD's hepatoprotective effect.
Tian‐Yu Yang, Chen Wang, Yi Ding, Wei‐Kang Zhang, Ling Zheng, Li Yue, Lei Zhang   +6 more
wiley   +1 more source

Dangguibuxue Decoction Attenuated AA I-Induced Renal Fibrosis: Integrating Network Pharmacology and Experimental Validation

Pharmaceuticals
Background: Dangguibuxue decoction (DD), containing Angelica sinensis (Oliv.) Diels (AS) and Astragalus membranaceus (Fisch.) Bge. (AM) (1:5), is a well-known traditional Chinese medicine (TCM) used for strengthening qi and nourishing the blood.
Suyan Liu, Jing Meng, Yong Zhao, Chunying Li, Yan Yi, Jiayin Han, Yushi Zhang, Chen Pan, Xingwen Wang, Liping Wang, Feng Gao, Xingnan Yue, Jingwen Wu, Hongmei Li, Aihua Liang   +14 more
doaj   +1 more source

Research Progress of Berberine in Kidney Disease: Targeting Mitochondria and Ferroptosis

iNew Medicine, EarlyView.
This figure illustrates the model‐specific renoprotective mechanisms of berberine (BBR) across three major kidney diseases. From left to right, the diagram shows that BBR targets distinct core pathways depending on the pathological context: in diabetic nephropathy (DN), BBR activates AMPK to improve mitochondrial energy metabolism; in acute kidney ...
Liuqing Wang, Rongyu Guo, Xiaojun Feng, Liqin Tang   +3 more
wiley   +1 more source

Biochemical and Molecular Insights Into Monocrotaline‐Induced Hepatotoxicity: An Experimental Mouse Study

Journal of Applied Toxicology, EarlyView.
ABSTRACT Monocrotaline (MCT), a plant‐derived pyrrolizidine alkaloid, is well known for its hepatotoxic effects. However, full elucidation of the mechanisms underlying MCT‐induced hepatotoxicity, as well as the development of reliable biomarkers for early detection and monitoring, requires an integrated evaluation of biochemical, molecular, and ...
Ali Şenol, Alparslan Kadir Devrim, Miyase Çinar, Mahmut Sözmen, Fatma Betül Akça   +4 more
wiley   +1 more source

Applications of Artificial Intelligence in the Detection of Traditional Chinese Herbal Medicines and Prepared Slices

中国工程科学
Currently, the market demand for traditional Chinese herbal medicines and prepared slices is experiencing rapid growth, rendering quality control and safety assurance even more pressing issues.
Wang Chaochao, Zhang Xianchao , Gu Zhengchang, Wang Jie   +3 more
doaj   +1 more source

Exposure‐Based Toxicological Evaluation of Lead and Elemental Impurities in Encapsulated Green Tea Dietary Supplements Under a Regulatory Framework

Journal of Applied Toxicology, EarlyView.
ABSTRACT The consumption of green tea (Camellia sinensis (L.) Kuntze) in the form of encapsulated dietary supplements has increased substantially in recent years; however, data supporting toxicological risk assessment of inorganic contaminants in these products remain limited.
Amanda da Silva Chaves, Lisia Maria Gobbo dos Santos, Beatriz Scaramelo, Júlia Maria Peixoto Loureiro, Fabio Coelho Amendoeira, Silvana do Couto Jacob, Fausto Klabund Ferraris   +6 more
wiley   +1 more source

Chinese Herbal Medicine [PDF]

The Australian Journal of Hospital Pharmacy, 2000
Anna Drew, Ian M Whyte, Andrew H Dawson, Alan Benoussan, Stephen P Myers   +4 more
openaire   +1 more source

Complementary and alternative medicine use by patients in pediatric gastroenterology clinics

JPGN Reports, EarlyView.
Abstract Objectives Use of complementary and alternative medicine (CAM) therapies among children seen in pediatric gastroenterology (GI) clinics is high. Multiple CAM therapies are effective as primary and adjuvant therapies for GI disorders and symptoms. Our study aimed to define the historical use of CAM and interest in CAM therapies in a specialized
Joshua D. Prozialeck, Lauren M. Potthoff, Bridget Whitehead, John E. Fortunato   +3 more
wiley   +1 more source

Establishment of a genome map-based karyotype of Artemisia argyi and identification of a new octoploid

Frontiers in Plant Science
Artemisia argyi, an essential plant in traditional Chinese medicine, encounters significant challenges in the development of germplasm resources and cytological research. This study employed the A. argyi reference genome to develop 20 repetitive sequence
Lina Li, Pei Du, Dahui Liu, Xiangyang Li, Guixiao La, Guixia Shi, Dandan Dai, Tiegang Yang   +7 more
doaj   +1 more source

Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives

JSFA reports, EarlyView.
Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz, Muhammad Tauseef Sultan, Muhammad Israr, Waqas Ahmad Khan, Fahad Tanveer, Muzzamal Hussain, Muhammad Imran, Ahmed Mujtaba, Anjuman Gul Memon, Muhammad Atif, Entessar Al Jbawi   +10 more
wiley   +1 more source