Results 1 to 10 of about 22,876 (205)

Altitudinal changes induce responses in Coptis chinensis Franch. rhizomes: endophytic communities, metabolite types, and alkaloid contents [PDF]

Frontiers in Plant Science
Coptis chinensis Franch. is a perennial medicinal plant with huge economic and social benefits, but how altitude affects the accumulation of bioactive compounds through microbial ecosystems remains unexplored.
Wenli Zhang, Wenli Zhang, Yanan Tang, Yanan Tang, Ran Luo, Ran Luo, Jiang He, Jiang He, Jie Yan, Fei Long, Longyun Li   +10 more
doaj   +3 more sources

1H-NMR-Based Metabonomics of the Protective Effect of Coptis chinensis and Berberine on Cinnabar-Induced Hepatotoxicity and Nephrotoxicity in Rats

Molecules, 2017
Coptis chinensis Franch has been used in Traditional Chinese Medicine (TCM) for treating infectious and inflammatory diseases for over two thousand years. Berberine (BN), an isoquinoline alkaloid, is the main component of Coptis chinensis.
Haifeng Wang, Gang Chen, Guang Yue Su
exaly   +4 more sources

Therapeutic potential of Coptis chinensis for arthritis with underlying mechanisms [PDF]

Frontiers in Pharmacology, 2023
Arthritis is a common degenerative disease of joints, which has become a public health problem affecting human health, but its pathogenesis is complex and cannot be eradicated. Coptis chinensis (CC) has a variety of active ingredients, is a natural antibacterial and anti-inflammatory drug.
Miaomiao Jiang
exaly   +5 more sources

Analysis of the Coptis chinensis genome reveals the diversification of protoberberine-type alkaloids [PDF]

Nature Communications, 2021
Coptis chinensis represents an early-diverging eudicot lineage with diverse medicinal applications. Here, the authors report its chromosome-scale genome assembly, infer a single ancient whole-genome duplication, and characterize the function of CYP719 in
Yifei Liu, Bo Wang, Shaohua Shu, Zheng Li, Chi Song, Di Liu, Yan Niu, Jinxin Liu, Jingjing Zhang, Heping Liu, Zhigang Hu, Bisheng Huang, Xiuyu Liu, Wei Liu, Liping Jiang, Mohammad Murtaza Alami, Yuxin Zhou, Yutao Ma, Xiangxiang He, Yicheng Yang, Tianyuan Zhang, Hui Hu, Michael S. Barker, Shilin Chen, Xuekui Wang, Jing Nie   +25 more
doaj   +4 more sources

Role of Coptis chinensis in antibiotic susceptibility of carbapenem-resistant Klebsiella pneumoniae

Journal of Microbiology, Immunology and Infection, 2022
Background: The incidence of carbapenem-resistant Klebsiella pneumoniae (CRKP) has rapidly increased. This study aimed to assess the effect of Coptis chinensis and its compounds on the minimal inhibitory concentrations (MICs) of eight antibiotics against
Cheng-Yin Tseng, Mao-Feng Sun, Tzu-Chien Kao, Tsai-Chung Li, Ching-Ting Lin   +4 more
doaj   +4 more sources

A biosynthetic network for protoberberine production in Coptis chinensis. [PDF]

Hortic Res, 2023
Abstract Protoberberine alkaloids are a group of tetracyclic isoquinoline compounds known for their well-established antimicrobial and anti-inflammatory properties. The richness and diversity of protoberberine alkaloids accumulated in the Coptis genus necessitate a comprehensive examination of the biosynthetic machinery to understand ...
Wu L, Zhao B, Deng Z, Wang B, Yu Y.
europepmc   +3 more sources

The effect of coptis chinensis on the signaling network in the squamous carcinoma cells

Frontiers in Bioscience - Elite, 2011
The effects of Coptis chinensis on the behavior of squamous cell carcinoma have not yet been established. We examined the anticancer activity of Coptis chinensis on human squamous carcinoma cells, both in vitro and in xenografted nude mice, and applied Pathway Array Technology to understand possible involvement of signaling pathways in Coptis Chinensis
Hongxia Wang
exaly   +3 more sources

Cytokine storm-calming property of the isoquinoline alkaloids in Coptis chinensis Franch. [PDF]

Front Pharmacol, 2022
Coronavirus disease (COVID-19) has spread worldwide and its effects have been more devastating than any other infectious disease. Importantly, patients with severe COVID-19 show conspicuous increases in cytokines, including interleukin (IL)-6, monocyte chemoattractant protein (MCP)-1, IL-8, tumor necrosis factor (TNF)-α, IL-1, IL-18, and IL-17, with ...
Lan Y, Wang H, Wu J, Meng X.
europepmc   +4 more sources

Wild wisdom meets cultivation: comparative rhizomicrobiome analysis unveils the key role of Paraburkholderia in growth promotion and disease suppression in Coptis chinensis [PDF]

Microbiome
Background The sustained monoculture and irregular planting practices rendered the cultivated Coptis chinensis more prone to various diseases compared to its wild counterparts. Rewilding the rhizomicrobiome of cultivated plants has emerged as a promising
Xianhe Cao, Qingjun Yuan, Chengcheng Hu, Hanxing Zhang, Xianyun Sun, Binbin Yan, Xiaojing Ma, Long Zhang, Luqi Huang, Shaojie Li, Zhenying Zhang   +10 more
doaj   +2 more sources

Determination of coptis chinensis’ quality by FT-NIR spectroscopy

Health, 2012
As a kind of traditional Chinese medicinal materials coptis chinensis has a lot of medicinal value and closely related to human health, Widely used in clinical or disease prevention and treatment. So the quality of medicinal coptis chinensis rapid determination is very important.
Jidong Yang, Zhenyao Liu, Bing Liu, Qianhua Zhu   +3 more
exaly   +2 more sources